dbPTM

PCMD1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PCMD1_MOUSE
UniProt AC	P59913
Protein Name	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
Gene Name	Pcmtd1
Organism	Mus musculus (Mouse).
Sequence Length	357
Subcellular Localization	Cytoplasm. Membrane Lipid-anchor .
Protein Description
Protein Sequence	MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGTPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDSKEEEEKEHIEAMKREEPPQNLLREKIMKLPLPESLKAYLTYFRDK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGGAVSAGE ------CCCCCCCCC	32.54	-
130	Ubiquitination	EKLESFIKNSDSFDK HHHHHHHHCCCCCCC	48.68	22790023
171	Ubiquitination	YCGAGVQKDHENYMK ECCCCCCCCHHHHHH	59.66	22790023
178	Ubiquitination	KDHENYMKILLKVGG CCHHHHHHHHHHCCC	21.60	22790023
224	Ubiquitination	APLVQPSKNDNGTPD CCCCCCCCCCCCCCC	75.02	22790023
266	Ubiquitination	INDEMQAKGIPQRAP CCHHHHHCCCCCCCC	40.24	22790023
302	Phosphorylation	LIPQPLDSEEDEKME ECCCCCCHHHHHHHH	51.04	27087446
312	Phosphorylation	DEKMEEDSKEEEEKE HHHHHHHCHHHHHHH	45.29	30352176
340	Ubiquitination	LLREKIMKLPLPESL HHHHHHHCCCCCHHH	50.88	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PCMD1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PCMD1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PCMD1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PCMD1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PCMD1_MOUSE

Related Literatures of Post-Translational Modification