PCDGH_HUMAN - dbPTM
PCDGH_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PCDGH_HUMAN
UniProt AC Q9Y5G0
Protein Name Protocadherin gamma-B5
Gene Name PCDHGB5
Organism Homo sapiens (Human).
Sequence Length 923
Subcellular Localization Cell membrane
Single-pass type I membrane protein.
Protein Description Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain..
Protein Sequence MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSDPQAELQFYLVVALALISVLFLLAVILAVALRLRRSSSPAAWSCFQPGLCVKSGPVVPPNYSQGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQDILCGDSSGALFPLCNSSESTSHPELQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MGSGAGELGR
-----CCCCHHHCCH		24.9521955146
70PhosphorylationTRKLRVSSEKPYFTV
CCEECCCCCCCEEEE		46.9417081983
74PhosphorylationRVSSEKPYFTVSAES
CCCCCCCEEEEEECC		23.9725907765
76PhosphorylationSSEKPYFTVSAESGE
CCCCCEEEEEECCCC		14.0125907765
78PhosphorylationEKPYFTVSAESGELL
CCCEEEEEECCCCEE		24.2225907765
81PhosphorylationYFTVSAESGELLVSS
EEEEEECCCCEEEEE		36.9725907765
87PhosphorylationESGELLVSSRLDREE
CCCCEEEEECCCHHH		15.0924719451
88PhosphorylationSGELLVSSRLDREEI
CCCEEEEECCCHHHH		29.4125907765
137PhosphorylationTPKFTQNSFELQISE
CCCCCCCEEEEEEEC		15.4118491316
392PhosphorylationEVPFKIISSSKNSYK
CCCEEEEECCCCEEE		31.84-
395AcetylationFKIISSSKNSYKLVT
EEEEECCCCEEEEEE		52.4319818219
399AcetylationSSSKNSYKLVTDGTL
ECCCCEEEEEECCCC		35.9819657541
414PhosphorylationDREQTPEYNVTITAT
CCCCCCCEEEEEEEE		19.0126503514
415N-linked_GlycosylationREQTPEYNVTITATD
CCCCCCEEEEEEEEC		23.85UniProtKB CARBOHYD
417PhosphorylationQTPEYNVTITATDRG
CCCCEEEEEEEECCC		14.6926503514
419PhosphorylationPEYNVTITATDRGKP
CCEEEEEEEECCCCC		17.7126503514
421PhosphorylationYNVTITATDRGKPPL
EEEEEEEECCCCCCC		19.9926503514
535PhosphorylationLQARDQGSPALSANV
EEECCCCCCCEEEEE		11.0225072903
539PhosphorylationDQGSPALSANVSLRV
CCCCCCEEEEEEEEE		21.6525072903
541N-linked_GlycosylationGSPALSANVSLRVLV
CCCCEEEEEEEEEEE		22.12UniProtKB CARBOHYD
651PhosphorylationDGGQPPLSATATLHL
CCCCCCCCCEEEEEE		29.37-
740PhosphorylationPVVPPNYSQGTLPYS
CCCCCCCCCCCCCCC		28.8624961811
746PhosphorylationYSQGTLPYSYNLCVA
CCCCCCCCCEEEEEE		27.2224961811
747PhosphorylationSQGTLPYSYNLCVAH
CCCCCCCCEEEEEEC		12.9524961811
810PhosphorylationPNTDWRFSQAQRPGT
CCCCCCCCCCCCCCC		18.9425003641
870PhosphorylationTMGLSARYGPQFTLQ
CCCCCCCCCCCEEEE		32.6425884760
875PhosphorylationARYGPQFTLQHVPDY
CCCCCCEEEEECCCC		21.9124961811
882PhosphorylationTLQHVPDYRQNVYIP
EEEECCCCCCCEEEC		14.1824927040
887PhosphorylationPDYRQNVYIPGSNAT
CCCCCCEEECCCCCE		14.6725884760
891PhosphorylationQNVYIPGSNATLTNA
CCEEECCCCCEECCC		20.2424719451
894PhosphorylationYIPGSNATLTNAAGK
EECCCCCEECCCCCC		38.0627050516
901UbiquitinationTLTNAAGKRDGKAPA
EECCCCCCCCCCCCC		42.4632142685
905UbiquitinationAAGKRDGKAPAGGNG
CCCCCCCCCCCCCCC		56.3332142685
914UbiquitinationPAGGNGNKKKSGKKE
CCCCCCCCCCCCCCC		64.0832142685
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PCDGH_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PCDGH_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PCDGH_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PCDGH_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PCDGH_HUMAN

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Related Literatures of Post-Translational Modification

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