PCDG7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PCDG7_HUMAN
• UniProt AC: Q9Y5G6
• Protein Name: Protocadherin gamma-A7
• Gene Name: PCDHGA7
• Organism: Homo sapiens (Human).
• Sequence Length: 932
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein.
• Protein Description: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain..
• Protein Sequence: MAAQPRGGDYRGFFLLSILLGTPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHKSRLLQASEGGLANVPTSHFVGMDGVQAFLQTYSHEVSLTADSRKSHLIFPQPNYVDMLISQESCEKNDSLLTSVDFQECKENLPSIQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
81	Phosphorylation	LFALNQRSGSLVTAG EEEEECCCCCEEECC	23.99	27251275
135	Phosphorylation	DNVPRFLTEEINVKI CCCCCCCCEECCEEE	28.94	24670416
397	Phosphorylation	LPFKLEKSIDNYYRL CCCEEEECCCCEEEE	26.29	-
401	Phosphorylation	LEKSIDNYYRLVTTK EEECCCCEEEEEEEC	6.04	18083107
402	Phosphorylation	EKSIDNYYRLVTTKN EECCCCEEEEEEECC	12.06	18083107
419	N-linked_Glycosylation	RETLSLYNITLKATD CCEEEEEEEEEEECC	26.51	UniProtKB CARBOHYD
429	Phosphorylation	LKATDGGTPPLSRET EEECCCCCCCCCCEE	27.54	26437602
433	Phosphorylation	DGGTPPLSRETHIFM CCCCCCCCCEEEEEE	33.57	24719451
545	N-linked_Glycosylation	GDPPLSSNMSLSLFV CCCCCCCCCEEEEEE	22.23	UniProtKB CARBOHYD
628	Phosphorylation	LYTGEVRTARALLDR EECCCHHHHHHHCCH	26.18	20068231
753	Phosphorylation	VQAFLQTYSHEVSLT HHHHHHHHCCEEEEC	8.62	25884760
758	Phosphorylation	QTYSHEVSLTADSRK HHHCCEEEECCCCCC	19.61	24961811
819	Phosphorylation	PNTDWRFSQAQRPGT CCCCCCCCCCCCCCC	18.94	25003641
879	Phosphorylation	TMGLSARYGPQFTLQ CCCCCCCCCCCEEEE	32.64	25884760
884	Phosphorylation	ARYGPQFTLQHVPDY CCCCCCEEEEECCCC	21.91	24961811
891	Phosphorylation	TLQHVPDYRQNVYIP EEEECCCCCCCEEEC	14.18	24927040
896	Phosphorylation	PDYRQNVYIPGSNAT CCCCCCEEECCCCCE	14.67	25884760
900	Phosphorylation	QNVYIPGSNATLTNA CCEEECCCCCEECCC	20.24	24719451
903	Phosphorylation	YIPGSNATLTNAAGK EECCCCCEECCCCCC	38.06	27050516
910	Ubiquitination	TLTNAAGKRDGKAPA EECCCCCCCCCCCCC	42.46	32142685
914	Ubiquitination	AAGKRDGKAPAGGNG CCCCCCCCCCCCCCC	56.33	32142685
923	Ubiquitination	PAGGNGNKKKSGKKE CCCCCCCCCCCCCCC	64.08	32142685

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PCDG7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PCDG7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PCDG7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PCDG7_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.