PCDG4_HUMAN - dbPTM
PCDG4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PCDG4_HUMAN
UniProt AC Q9Y5G9
Protein Name Protocadherin gamma-A4
Gene Name PCDHGA4
Organism Homo sapiens (Human).
Sequence Length 962
Subcellular Localization Cell membrane
Single-pass type I membrane protein.
Protein Description Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain..
Protein Sequence MHFILDPEDPGAPQASTEGKPKHRRLRGGVVMAAPPARPDHTRLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRKVRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHDGPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAEGSRLAGVPASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFSQPSYADTLISRESCEKSEPLLITQDLLETKGDPNLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
320PhosphorylationRKVRDKISQLFQLNS
HHHHHHHHHHHHHHC		36.2223879269
329PhosphorylationLFQLNSLSGDITILG
HHHHHCCCCCEEEEC		25.7423879269
333PhosphorylationNSLSGDITILGGLDY
HCCCCCEEEECCCCC		5.6823879269
419N-linked_GlycosylationLVTCSIPDNLPFTLE
EEEEECCCCCCEEEE		21.28UniProtKB CARBOHYD
428PhosphorylationLPFTLEKTYGNYYRL
CCEEEEEHHCCHHHH		42.8924043423
429PhosphorylationPFTLEKTYGNYYRLL
CEEEEEHHCCHHHHE		18.9924043423
432PhosphorylationLEKTYGNYYRLLTHR
EEEHHCCHHHHEEEC		11.8724043423
433PhosphorylationEKTYGNYYRLLTHRT
EEHHCCHHHHEEECE		29.9424043423
437PhosphorylationGNYYRLLTHRTLDRE
CCHHHHEEECEECHH		11.0425072903
440PhosphorylationYRLLTHRTLDREEVS
HHHEEECEECHHHHH		4.3825072903
450N-linked_GlycosylationREEVSEYNITVTATD
HHHHHEEEEEEEEEC		53.58-
458PhosphorylationITVTATDQGTPPLST
EEEEEECCCCCCCCC		16.46-
470PhosphorylationLSTETHISLQVMDIN
CCCCCEEEEEEEECC		27.21-
489PhosphorylationTFPHASYSAYIPENN
CCCCCEEEEECCCCC		10.18-
501PhosphorylationENNPRGASILSMTAQ
CCCCCCCEEEEEEEE		5.42-
545N-linked_GlycosylationINSNTGILYALCSFD
EECCCCCEEEEECCC		24.83UniProtKB CARBOHYD
576N-linked_GlycosylationGDPPLSSNVSLSLFV
CCCCCCCCEEEEEEE		40.33-
589PhosphorylationFVLDQNDNVPEILYP
EEEECCCCCCCEEEE		18.61-
605PhosphorylationFPTDGSTGVELAPRS
CCCCCCCCCEECCCC		11.2822199227
606PhosphorylationPTDGSTGVELAPRSA
CCCCCCCCEECCCCC		10.9322199227
620PhosphorylationADSGYLVTKVVAVDR
CCCCEEEEEEEEEEC		14.33-
628PhosphorylationKVVAVDRDSGQNAWL
EEEEEECCCCCCEEH		26.18-
636PhosphorylationSGQNAWLSYSLLKSS
CCCCEEHHHHHHHCC		56.7922199227
637PhosphorylationGQNAWLSYSLLKSSE
CCCEEHHHHHHHCCC		19.9724719451
638PhosphorylationQNAWLSYSLLKSSEP
CCEEHHHHHHHCCCC		5.9424719451
659PhosphorylationLHTGEVRTARALLDR
EECCCHHHHHHHHCH		16.6220068231
753PhosphorylationKLRRWHKSRLLHAEG
HHHHHHHHHHHCCCC		8.62-
761PhosphorylationRLLHAEGSRLAGVPA
HHHCCCCCCCCCCCH		20.3426699800
769PhosphorylationRLAGVPASHFVGVDG
CCCCCCHHHCCCCHH		2.3326699800
784PhosphorylationVRAFLQTYSHEVSLT
HHHHHHHHCCEEEEC		26.8525884760
789PhosphorylationQTYSHEVSLTADSRK
HHHCCEEEECCCCCC		51.5424961811
849PhosphorylationPNTDWRFSQAQRPGT
CCCCCCCEECCCCCC		5.3025003641
878PhosphorylationNQFDTEMLQAMILAS
CCCCHHHHHHHHHHH		32.64-
890PhosphorylationLASASEAADGSSTLG
HHHHHHHCCCCCCCC		14.18-
895PhosphorylationEAADGSSTLGGGAGT
HHCCCCCCCCCCCCC		14.67-
909PhosphorylationTMGLSARYGPQFTLQ
CCCCCCCCCCCEEEE		42.4625884760
914PhosphorylationARYGPQFTLQHVPDY
CCCCCCEEEEECCCC		12.5224961811
921PhosphorylationTLQHVPDYRQNVYIP
EEEECCCCCCCEEEC		57.9024927040
926PhosphorylationPDYRQNVYIPGSNAT
CCCCCCEEECCCCCE		54.6725884760
930PhosphorylationQNVYIPGSNATLTNA
CCEEECCCCCEECCC		73.0724719451
933PhosphorylationYIPGSNATLTNAAGK
EECCCCCEECCCCCC		27050516
940UbiquitinationTLTNAAGKRDGKAPA
EECCCCCCCCCCCCC		32142685
944UbiquitinationAAGKRDGKAPAGGNG
CCCCCCCCCCCCCCC		32142685
953UbiquitinationPAGGNGNKKKSGKKE
CCCCCCCCCCCCCCC		32142685
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PCDG4_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PCDG4_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PCDG4_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PCDG4_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PCDG4_HUMAN

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Related Literatures of Post-Translational Modification

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