| UniProt ID | PCDB3_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y5E6 | |
| Protein Name | Protocadherin beta-3 | |
| Gene Name | PCDHB3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 796 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.. | |
| Protein Sequence | MEAGGERFLRQRQVLLLFVFLGGSLAGSESRRYSVAEEKEKGFLIANLAKDLGLRVEELAARGAQVVSKGNKQHFQLSHQTGDLLLNEKLDREELCGPTEPCILHFQILLQNPLQFVTNELRIIDVNDHSPVFFENEMHLKILESTLPGTVIPLGNAEDLDVGRNSLQNYTITPNSHFHVLTRSRRDGRKYPELVLDKALDREEQPELSLTLTALDGGSPPRSGTAQINIQVLDINDNAPEFAQPLYEVAVLENTPVNSVIVTVSASDLDTGSFGTISYAFFHASEEIRKTFQLNPITGDMQLVKYLNFEAINSYEVDIEAKDGGGLSGKSTVIVQVVDVNDNPPELTLSSVNSPIPENSGETVLAVFSVSDLDSGDNGRVMCSIENNLPFFLKPSVENFYTLVSEGALDRETRSEYNITITITDLGTPRLKTKYNITVLVSDVNDNAPAFTQISYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGQMVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQGAERVSEANPSFRKSFEFS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 34 | Phosphorylation | GSESRRYSVAEEKEK CCHHHCCCHHHHHHH | 17.03 | 28348404 | |
| 68 | Phosphorylation | ARGAQVVSKGNKQHF HCCCEEEECCCHHEE | 35.67 | - | |
| 169 | N-linked_Glycosylation | VGRNSLQNYTITPNS CCCCCCCCEEECCCC | 41.00 | UniProtKB CARBOHYD | |
| 191 | Phosphorylation | SRRDGRKYPELVLDK CCCCCCCCCHHHHHH | 10.69 | 19658100 | |
| 402 | Phosphorylation | PSVENFYTLVSEGAL CCHHHHHHHHHCCCC | 19.29 | 21949786 | |
| 405 | Phosphorylation | ENFYTLVSEGALDRE HHHHHHHHCCCCCCC | 33.16 | 21949786 | |
| 418 | N-linked_Glycosylation | RETRSEYNITITITD CCCCCEEEEEEEEEE | 22.37 | UniProtKB CARBOHYD | |
| 436 | N-linked_Glycosylation | PRLKTKYNITVLVSD CCCEEEEEEEEEEEC | 25.63 | UniProtKB CARBOHYD | |
| 567 | N-linked_Glycosylation | FVLYPLQNGSAPCTE EEEEECCCCCCCCCC | 54.81 | UniProtKB CARBOHYD | |
| 765 | Ubiquitination | GSGTNEFKFLKPIIP CCCCCCEECCCCCCC | 43.54 | 23000965 | |
| 768 | Ubiquitination | TNEFKFLKPIIPNFV CCCEECCCCCCCHHH | 36.98 | 23000965 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCDB3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCDB3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCDB3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PCDB3_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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