| UniProt ID | PCDAD_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y5I0 | |
| Protein Name | Protocadherin alpha-13 | |
| Gene Name | PCDHA13 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 950 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.. | |
| Protein Sequence | MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MLSSWQGGPR -----CCCCCCCCCC | 28.38 | 26270265 | |
| 4 | Phosphorylation | ----MLSSWQGGPRP ----CCCCCCCCCCH | 21.32 | 26270265 | |
| 33 | Phosphorylation | TGSGQLHYSVPEEAK HCCCCCCCCCCHHHC | 21.69 | - | |
| 136 | Phosphorylation | NPPIFPESKKRIIIA CCCCCCHHCCEEEEE | 43.65 | 22985185 | |
| 193 | Phosphorylation | LEQMSSLSLVLRKTL HHHHHHHHHHHHHCC | 20.55 | 24719451 | |
| 257 | N-linked_Glycosylation | TVLENAFNGTLVIKL EEEECCCCCEEEEEE | 39.88 | UniProtKB CARBOHYD | |
| 265 | N-linked_Glycosylation | GTLVIKLNATDPDDG CEEEEEEEEECCCCC | 35.47 | UniProtKB CARBOHYD | |
| 356 | Phosphorylation | EVTITSLSLPIREDT EEEEEEEEEECCCCC | 31.69 | 24719451 | |
| 379 | Phosphorylation | ISVSDRDSGSNGQVT EEECCCCCCCCCEEE | 45.04 | 25954137 | |
| 381 | Phosphorylation | VSDRDSGSNGQVTCT ECCCCCCCCCEEEEE | 41.56 | 25954137 | |
| 386 | Phosphorylation | SGSNGQVTCTLTPHV CCCCCEEEEEECCCC | 7.59 | 25954137 | |
| 388 | Phosphorylation | SNGQVTCTLTPHVPF CCCEEEEEECCCCCE | 25.05 | 25954137 | |
| 432 | Phosphorylation | VTARDGGSPSLWATA EEECCCCCCCEEEEE | 19.49 | - | |
| 506 | Phosphorylation | VGERALSSYVSVHAE HHHHHHHHEEEEEEC | 30.33 | - | |
| 514 | Phosphorylation | YVSVHAESGKVYALQ EEEEEECCCCEEEEC | 44.70 | 29759185 | |
| 548 | N-linked_Glycosylation | GVPPLGSNVTLQVFV CCCCCCCCEEEEEEE | 29.06 | UniProtKB CARBOHYD | |
| 601 | Phosphorylation | VRAVDADSGYNAWLS EEEEECCCCCCEEEE | 44.92 | 18187866 | |
| 603 | Phosphorylation | AVDADSGYNAWLSYE EEECCCCCCEEEEHH | 12.98 | - | |
| 802 (in isoform 2) | Phosphorylation | - | 56.45 | - | |
| 808 | Phosphorylation | QPNPDWRYSASLRAG CCCCCCCCEEHHHCC | 12.34 | 20736484 | |
| 809 | Phosphorylation | PNPDWRYSASLRAGM CCCCCCCEEHHHCCC | 11.65 | 24719451 | |
| 811 | Phosphorylation | PDWRYSASLRAGMHS CCCCCEEHHHCCCCC | 16.67 | 24719451 | |
| 818 | Phosphorylation | SLRAGMHSSVHLEEA HHHCCCCCCEEHHHC | 25.76 | 28857561 | |
| 819 | Phosphorylation | LRAGMHSSVHLEEAG HHCCCCCCEEHHHCC | 10.01 | 24719451 | |
| 877 | Ubiquitination | KYGPGNPKQSGPGEL ECCCCCCCCCCCCCC | 62.18 | 33845483 | |
| 893 | Phosphorylation | DKFIIPGSPAIISIR CCEEECCCCEEEEEE | 13.05 | 27050516 | |
| 898 | Phosphorylation | PGSPAIISIRQEPTN CCCCEEEEEECCCCC | 12.95 | 27732954 | |
| 904 | Phosphorylation | ISIRQEPTNSQIDKS EEEECCCCCCCCCHH | 46.91 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCDAD_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCDAD_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCDAD_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PCDAD_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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