PCD18_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PCD18_MOUSE
• UniProt AC: Q8VHR0
• Protein Name: Protocadherin 18
• Gene Name: Pcdh18
• Organism: Mus musculus (Mouse).
• Sequence Length: 1134
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein.
• Protein Description: Potential calcium-dependent cell-adhesion protein..
• Protein Sequence: MHQMNTKMHFRFALALLMAFFSHDVLAKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSAVRFRAMPRGNSPLLVVNENTGEISIGAKIDREQLCQKNLNCSIEFDVLTLPTEHLQLFHIEVDVLDINDNSPQFSRPVIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDYFNIEVRTRTDGAKYAELIVVKELDRELKASYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQPSYTIQLLENSPVGTLLLDLNATDPDEGANGRIVYSFSSHVSPKIIETFKIDSEKGHLTLFKPVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEISINLMSPGKEEVSYVFEGDPIDTFVAIVRVQDKDSGLNGEIICKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDKGTPSLSSVRHFTVQINDINDNPPRFQRSRYEFVISENNSPGAYITTVTATDPDLGENGHVTYTILESFVLGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSQKQLSSNTTVVLTIIDENDNVPVVIGPAMHNNTAEISIPKGAESGFHVTRIRVVDRDSGANAEFSCSIVSGNEENIFIMDPRSCDIHTNVSMESIPSAEWALSVIIQDKGSPPLHTKVLLRCMVFDYAESVTSTAMTSVSRASLDVSMIIIISLGAICAVLLVIMVLFATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEVSQLLSMLHQGQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPAQPQQQHSHQGLDDDSQPAENGEKKKSFSTFGKDSPSDEDSGDSSTSSLLSEMSSVFQRLLPASLDTFSECNEGDRSNSLERRKGPAQGKTGGYPQGVAAWAASTHFQNPTSSSGTPLGTHSSVQPSSKWLPAMEEIPENYEEDDFDNVLNHLSDGKHELMDASELVAEINKLLQDVRQS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
103	N-linked_Glycosylation	QLCQKNLNCSIEFDV HHHHHCCCCEEEEEE	27.21	-
149	Phosphorylation	IPIEISESAAVGTRI EEEEECCCCCCCCCC	18.10	21454597
154	Phosphorylation	SESAAVGTRIPLDSA CCCCCCCCCCCCCCC	20.87	21454597
219	Phosphorylation	YELQLTASDMGVPQR EEEEEEHHHCCCCCC	23.93	-
269	N-linked_Glycosylation	GTLLLDLNATDPDEG EEEEEECCCCCCCCC	40.22	-
559	N-linked_Glycosylation	SQKQLSSNTTVVLTI CCCEECCCCEEEEEE	36.07	-
679	Phosphorylation	LRCMVFDYAESVTST HHHHHHHHHHHHHHH	10.78	-
682	Phosphorylation	MVFDYAESVTSTAMT HHHHHHHHHHHHHHH	23.64	-
741	Phosphorylation	YNCRVAESTYQHHPK CCCEEECHHHCCCCC	23.76	27149854
743	Phosphorylation	CRVAESTYQHHPKRP CEEECHHHCCCCCCC	18.35	29514104
751	Phosphorylation	QHHPKRPSRQIHKGD CCCCCCCCCCEECCC	40.63	29514104
760	Phosphorylation	QIHKGDITLVPTING CEECCCEEEEEEECC	26.83	22345495
764	Phosphorylation	GDITLVPTINGTLPI CCEEEEEEECCCCCC	21.42	22345495
768	Phosphorylation	LVPTINGTLPIRSHH EEEEECCCCCCCCCC	25.52	26824392
773	Phosphorylation	NGTLPIRSHHRSSPS CCCCCCCCCCCCCCC	25.10	27717184
777	Phosphorylation	PIRSHHRSSPSSSPT CCCCCCCCCCCCCCC	42.09	24899341
778	Phosphorylation	IRSHHRSSPSSSPTL CCCCCCCCCCCCCCC	28.85	25521595
780	Phosphorylation	SHHRSSPSSSPTLER CCCCCCCCCCCCCCC	45.45	25521595
781	Phosphorylation	HHRSSPSSSPTLERG CCCCCCCCCCCCCCC	43.66	23737553
782	Phosphorylation	HRSSPSSSPTLERGQ CCCCCCCCCCCCCCC	26.66	24899341
784	Phosphorylation	SSPSSSPTLERGQMG CCCCCCCCCCCCCCC	43.10	23737553
868	Phosphorylation	LQDMDKFSLKDSGRG CCCHHHCCCCCCCCC	40.00	22817900
877	Phosphorylation	KDSGRGDSEAGDSDY CCCCCCCCCCCCCCC	31.97	25338131
882	Phosphorylation	GDSEAGDSDYDLGRD CCCCCCCCCCCCCCC	36.83	26370283
884	Phosphorylation	SEAGDSDYDLGRDSP CCCCCCCCCCCCCCH	19.61	29899451
890	Phosphorylation	DYDLGRDSPIDRLLG CCCCCCCCHHHHHHC	23.53	25521595
937	Phosphorylation	CWMPPLPSPSSDYRS CCCCCCCCCCCCCCC	45.13	22942356
983	Phosphorylation	GEKKKSFSTFGKDSP CCCCCCCCCCCCCCC	29.89	29899451
991	Phosphorylation	TFGKDSPSDEDSGDS CCCCCCCCCCCCCCC	58.55	25338131
1031	Phosphorylation	ECNEGDRSNSLERRK CCCCCCCCCCCCCCC	35.19	25338131
1033	Phosphorylation	NEGDRSNSLERRKGP CCCCCCCCCCCCCCC	32.62	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PCD18_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PCD18_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PCD18_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PCD18_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.