PC11X_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PC11X_HUMAN
• UniProt AC: Q9BZA7
• Protein Name: Protocadherin-11 X-linked
• Gene Name: PCDH11X
• Organism: Homo sapiens (Human).
• Sequence Length: 1347
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Potential calcium-dependent cell-adhesion protein..
• Protein Sequence: MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	N-linked_Glycosylation	HSGAQEKNYTIREEM CCCCHHCCCCCCHHC	38.13	UniProtKB CARBOHYD
29	Phosphorylation	GAQEKNYTIREEMPE CCHHCCCCCCHHCCC	23.97	24719451
48	N-linked_Glycosylation	GDLLKDLNLSLIPNK HHHHHHCCCCCCCCC	37.40	UniProtKB CARBOHYD
54	N-linked_Glycosylation	LNLSLIPNKSLTTAM CCCCCCCCCCCCHHH	39.28	UniProtKB CARBOHYD
69	Phosphorylation	QFKLVYKTGDVPLIR EEEEEEECCCCCEEE	22.41	22985185
181	Phosphorylation	QNYELIKSQNIFGLD CCHHHHHCCCEECCE	22.82	28122231
192	Phosphorylation	FGLDVIETPEGDKMP ECCEEEECCCCCCCC	18.60	28122231
218	Acetylation	EKDTYVMKVKVEDGG HCCEEEEEEEECCCC	28.94	7978747
242	Phosphorylation	LQVSVTDTNDNHPVF EEEEEECCCCCCCEE	34.80	-
344	N-linked_Glycosylation	ARAMVLVNVTDVNDN CEEEEEEEEECCCCC	27.15	UniProtKB CARBOHYD
514	Phosphorylation	PDAPPEFSLDCRTGM CCCCCCCCCCCCCCC	22.95	22210691
523	Phosphorylation	DCRTGMLTVVKKLDR CCCCCCEEEEECCCC	17.86	22210691
553	N-linked_Glycosylation	GVPPLTSNVTVFVSI CCCCCCCCEEEEEEE	28.39	UniProtKB CARBOHYD
638	Phosphorylation	FDREKQESYTFYVKA CCCCCCCEEEEEEEE	27.29	20068231
639	Phosphorylation	DREKQESYTFYVKAE CCCCCCEEEEEEEEC	10.50	20068231
640	Phosphorylation	REKQESYTFYVKAED CCCCCEEEEEEEECC	20.12	20068231
642	Phosphorylation	KQESYTFYVKAEDGG CCCEEEEEEEECCCC	8.01	20068231
652	Phosphorylation	AEDGGRVSRSSSAKV ECCCCCEECCCCCEE	25.69	20068231
773	N-linked_Glycosylation	VIVNLFVNESVTNAT EEEEHHCCCCCCCHH	28.61	UniProtKB CARBOHYD
807	Phosphorylation	IADVSSPTSDYVKIL ECCCCCCCHHHHHHH	35.86	-
856	O-linked_Glycosylation	KQNSEWATPNPENRQ HCCCCCCCCCHHHHH	25.36	55835487
915	Phosphorylation	PIDLEEQTMGKYNWV CCCHHHCCCCCCCCC	31.04	27134283
923	Phosphorylation	MGKYNWVTTPTTFKP CCCCCCCCCCCCCCC	20.76	24719451
924	Phosphorylation	GKYNWVTTPTTFKPD CCCCCCCCCCCCCCC	14.71	28348404
926	Phosphorylation	YNWVTTPTTFKPDSP CCCCCCCCCCCCCCH	42.65	28348404
927	Phosphorylation	NWVTTPTTFKPDSPD CCCCCCCCCCCCCHH	30.75	28348404
932	Phosphorylation	PTTFKPDSPDLARHY CCCCCCCCHHHHHHH	28.92	24719451
941	Phosphorylation	DLARHYKSASPQPAF HHHHHHHCCCCCCCC	27.15	-
943	Phosphorylation	ARHYKSASPQPAFQI HHHHHCCCCCCCCCC	31.03	24719451
954	Phosphorylation	AFQIQPETPLNSKHH CCCCCCCCCCCCCCC	39.50	24719451
1062 (in isoform 6)	Phosphorylation	-	66.50	-
1104	Phosphorylation	RATPSNRTEGDGNSD CCCCCCCCCCCCCCC	48.87	-
1110	Phosphorylation	RTEGDGNSDPESTFI CCCCCCCCCHHHCCC	61.13	-
1114	Phosphorylation	DGNSDPESTFIPGLK CCCCCHHHCCCCCHH	33.72	-
1115	Phosphorylation	GNSDPESTFIPGLKK CCCCHHHCCCCCHHH	24.75	-
1317	Phosphorylation	RLHPSDDSIKVIPLT CCCCCCCCCEEEECC	29.33	26074081
1324	Phosphorylation	SIKVIPLTTFTPRQQ CCEEEECCCCCHHHH	17.95	26074081
1325	Phosphorylation	IKVIPLTTFTPRQQA CEEEECCCCCHHHHC	32.94	26074081
1327	Phosphorylation	VIPLTTFTPRQQARP EEECCCCCHHHHCCC	18.57	26074081
1339	Phosphorylation	ARPSRGDSPIMEEHP CCCCCCCCCCCCCCC	21.10	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PC11X_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PC11X_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PC11X_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PC11X_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.