dbPTM

PBX4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PBX4_HUMAN
UniProt AC	Q9BYU1
Protein Name	Pre-B-cell leukemia transcription factor 4
Gene Name	PBX4
Organism	Homo sapiens (Human).
Sequence Length	374
Subcellular Localization	Nucleus .
Protein Description
Protein Sequence	MAAPPRPAPSPPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATASPAGDPGSINSSTSN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	APPRPAPSPPAPRRL CCCCCCCCCCCCCCC	45.69	23312004
19	Phosphorylation	PAPRRLDTSDVLQQI CCCCCCCHHHHHHHH	31.27	27251275
20	Phosphorylation	APRRLDTSDVLQQIM CCCCCCHHHHHHHHH	25.95	27251275
30	Phosphorylation	LQQIMAITDQSLDEA HHHHHHHCCCCCCHH	20.60	27251275
33	Phosphorylation	IMAITDQSLDEAQAR HHHHCCCCCCHHHHH	40.37	27251275
55	Phosphorylation	RMKPALFSVLCEIKE HCCHHHHHHHHHCCC	18.28	24719451
153	Phosphorylation	EQACREFTTHVTNLL HHHHHHHHHHHHHHH	15.96	-
184	Ubiquitination	MVGAIHGKFSAIQMQ HHHHHHHHHHHHHHH	23.22	-
255	Phosphorylation	RKGGLTISQVSNWFG HCCCCCHHHHHHHHC	21.21	-
258	Phosphorylation	GLTISQVSNWFGNKR CCCHHHHHHHHCCCE	22.24	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PBX4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PBX4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PBX4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PBX4_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PBX4_HUMAN

Related Literatures of Post-Translational Modification