PAX2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PAX2_MOUSE
• UniProt AC: P32114
• Protein Name: Paired box protein Pax-2
• Gene Name: Pax2
• Organism: Mus musculus (Mouse).
• Sequence Length: 414
• Subcellular Localization: Nucleus.
• Protein Description: Transcription factor that may have a role in kidney cell differentiation..
• Protein Sequence: MDMHCKADPFSAMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASANPELGSNVSGTQTYPVVTGRDMTSTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAYDRH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	Phosphorylation	VSKILGRYYETGSIK HHHHHCCHHCCCCCC	12.12	-
225	Phosphorylation	GGLHLVWTLRDVSEG CCEEEEEEEEECCCC	12.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PAX2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PAX2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PAX2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RB_MOUSE	Rb1	physical	12200151

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.