dbPTM

PARG1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PARG1_ARATH
UniProt AC	Q9SKB3
Protein Name	Poly(ADP-ribose) glycohydrolase 1
Gene Name	PARG1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	548
Subcellular Localization
Protein Description	Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (By similarity). Involved in establishing period length of the circadian oscillator. May regulate post-translational poly(ADP-ribosyl)ation of an oscillator component..
Protein Sequence	MENREDLNSILPYLPLVIRSSSLYWPPRVVEALKAMSEGPSHSQVDSGEVLRQAIFDMRRSLSFSTLEPSASNGYAFLFDELIDEKESKRWFDEIIPALASLLLQFPSLLEVHFQNADNIVSGIKTGLRLLNSQQAGIVFLSQELIGALLACSFFCLFPDDNRGAKHLPVINFDHLFASLYISYSQSQESKIRCIMHYFERFCSCVPIGIVSFERKITAAPDADFWSKSDVSLCAFKVHSFGLIEDQPDNALEVDFANKYLGGGSLSRGCVQEEIRFMINPELIAGMLFLPRMDDNEAIEIVGAERFSCYTGYASSFRFAGEYIDKKAMDPFKRRRTRIVAIDALCTPKMRHFKDICLLREINKALCGFLNCSKAWEHQNIFMDEGDNEIQLVRNGRDSGLLRTETTASHRTPLNDVEMNREKPANNLIRDFYVEGVDNEDHEDDGVATGNWGCGVFGGDPELKATIQWLAASQTRRPFISYYTFGVEALRNLDQVTKWILSHKWTVGDLWNMMLEYSAQRLYKQTSVGFFSWLLPSLATTNKAIQPP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of PARG1_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PARG1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PARG1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PARG1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PARP2_ARATH	PP	physical	25569773
PARP1_ARATH	PARP1	physical	25950582
PARP2_ARATH	PP	physical	25950582

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PARG1_ARATH

Related Literatures of Post-Translational Modification