| UniProt ID | PAR6G_MOUSE | |
|---|---|---|
| UniProt AC | Q9JK84 | |
| Protein Name | Partitioning defective 6 homolog gamma | |
| Gene Name | Pard6g | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 382 | |
| Subcellular Localization | Cytoplasm. Cell membrane. Cell junction, tight junction. | |
| Protein Description | Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity).. | |
| Protein Sequence | MNRSFHKSQTLRFYDCSAVEVKSKFGAEFRRFSLDRHKPGKFEDFYQLVVHTHHISNTEVTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEADHYSFGAGTLSRKKKVLVTLRDDGLRRRPHLNISMPHDFRPVSSIIDVDILPETHRRVRLYRHGYEKPLGFYIRDGTSVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRSSRTSGSSVHSTDSTTSHHSLPGAHVLQNSEDVESDEEADIVIEGALEPQHIPKTQAVPPGSLSRANGTSLAHGLHRRDMSLHSSGRESNGSIHRFLSSLKPDPRHSLVLPQGGVEEHGPAITL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MNRSFHKSQTL ----CCCCCCCCCEE | 27.05 | 29514104 | |
| 8 | Phosphorylation | MNRSFHKSQTLRFYD CCCCCCCCCEEEEEE | 21.59 | 28507225 | |
| 10 | Phosphorylation | RSFHKSQTLRFYDCS CCCCCCCEEEEEECC | 27.30 | 25777480 | |
| 104 | Phosphorylation | KREEADHYSFGAGTL CHHHCCCCCCCCCCC | 13.27 | 29514104 | |
| 110 | Phosphorylation | HYSFGAGTLSRKKKV CCCCCCCCCCCCCEE | 22.49 | 26824392 | |
| 112 | Phosphorylation | SFGAGTLSRKKKVLV CCCCCCCCCCCEEEE | 41.72 | 29514104 | |
| 189 | Ubiquitination | VTPHGLEKVPGIFIS ECCCCCCCCCCEEEE | 59.79 | - | |
| 293 | Phosphorylation | QNSEDVESDEEADIV CCCCCCCCHHHCCEE | 50.61 | 25338131 | |
| 320 | Phosphorylation | TQAVPPGSLSRANGT CCCCCCCCCCCCCCC | 29.01 | 25338131 | |
| 322 | Phosphorylation | AVPPGSLSRANGTSL CCCCCCCCCCCCCCH | 30.92 | 25338131 | |
| 343 | Phosphorylation | RDMSLHSSGRESNGS CCCCCCCCCCCCCCC | 30.99 | 28507225 | |
| 347 | Phosphorylation | LHSSGRESNGSIHRF CCCCCCCCCCCHHHH | 45.17 | 25338131 | |
| 350 | Phosphorylation | SGRESNGSIHRFLSS CCCCCCCCHHHHHHH | 21.33 | 25338131 | |
| 365 | Phosphorylation | LKPDPRHSLVLPQGG CCCCCCCEEECCCCC | 22.81 | 26824392 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PAR6G_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PAR6G_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PAR6G_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PAR6G_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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