dbPTM

PAQR7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PAQR7_HUMAN
UniProt AC	Q86WK9
Protein Name	Membrane progestin receptor alpha {ECO:0000303\|PubMed:23763432}
Gene Name	PAQR7 {ECO:0000312\|HGNC:HGNC:23146}
Organism	Homo sapiens (Human).
Sequence Length	346
Subcellular Localization	Cell membrane Multi-pass membrane protein .
Protein Description	Plasma membrane progesterone (P4) receptor coupled to G proteins. [PubMed: 23763432 Seems to act through a G(i) mediated pathway]
Protein Sequence	MAMAQKLSHLLPSLRQVIQEPQLSLQPEPVFTVDRAEVPPLFWKPYIYAGYRPLHQTWRFYFRTLFQQHNEAVNVWTHLLAALVLLLRLALFVETVDFWGDPHALPLFIIVLASFTYLSFSALAHLLQAKSEFWHYSFFFLDYVGVAVYQFGSALAHFYYAIEPAWHAQVQAVFLPMAAFLAWLSCIGSCYNKYIQKPGLLGRTCQEVPSVLAYALDISPVVHRIFVSSDPTTDDPALLYHKCQVVFFLLAAAFFSTFMPERWFPGSCHVFGQGHQLFHIFLVLCTLAQLEAVALDYEARRPIYEPLHTHWPHNFSGLFLLTVGSSILTAFLLSQLVQRKLDQKTK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
13	Phosphorylation	KLSHLLPSLRQVIQE HHHHHHHHHHHHHHC	24719451
193	Ubiquitination	CIGSCYNKYIQKPGL HHHHHHHHHCCCCCC	22817900
194	Phosphorylation	IGSCYNKYIQKPGLL HHHHHHHHCCCCCCC	-
197	Ubiquitination	CYNKYIQKPGLLGRT HHHHHCCCCCCCCCC	21906983
197	Ubiquitination	CYNKYIQKPGLLGRT HHHHHCCCCCCCCCC	21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PAQR7_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PAQR7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PAQR7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PAQR7_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PAQR7_HUMAN

Related Literatures of Post-Translational Modification