dbPTM

PAPS3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PAPS3_ARATH
UniProt AC	Q56XM9
Protein Name	Nuclear poly(A) polymerase 3 {ECO:0000303\|PubMed:18479511}
Gene Name	PAPS3 {ECO:0000303\|PubMed:18479511}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	507
Subcellular Localization	Nucleus .
Protein Description	Essential protein. [PubMed: 19956626 Polymerase that creates the 3'-poly(A) tail of mRNA's]
Protein Sequence	MKKGGGRNKGFPQDDESSISLRQLMVNEGLIPSLEDEVKRRGVINQLRKIVVRWVKNVAWQHRLPQNQIDATNATILPYGSYGLGVYGSESDIDALCIGPFFASIAEDFFISLRDMLKSRREVSELHCVKDAKVPLIRFKFDGILVDLPYAQLRVLSIPNNVDVLNPFFLRDIDETSWKILSGVRANKCILQLVPSLELFQSLLRCVKLWAKRRGVYGNLNGFLGGVHMAILAAFVCGYQPNATLSSLLANFFYTFAHWQWPTPVVLLEDTYPSTGAPPGLMPIQLPCGSHQYCNSTITRSTFYKIVAEFLLGHNLTKDYLKLNFSWKDLFELYPYANTYTWFTKIHLSAANQEDLSDWVGWVKSRFRCLLIKIEEVYGICDPNPTEYVETYTKQPNIVFYWGLQLRTINVSDIESVKIDFLKNVNSGSFRGTVGRIQLTLVKASQLPKNGECGSNNRSKKVTKTCWRIREDKQCNNVPVYSKHLPGYVVGYQKMVNREADGMEVKC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
326	Phosphorylation	DYLKLNFSWKDLFEL HHHCCCCCHHHHHHH	23111157
339	Phosphorylation	ELYPYANTYTWFTKI HHCCCCCCEEEEEEE	23111157
340	Phosphorylation	LYPYANTYTWFTKIH HCCCCCCEEEEEEEE	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PAPS3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PAPS3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PAPS3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
CPSF_ARATH	CPSF30	physical	18479511

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PAPS3_ARATH

Related Literatures of Post-Translational Modification