| UniProt ID | PANK3_HUMAN | |
|---|---|---|
| UniProt AC | Q9H999 | |
| Protein Name | Pantothenate kinase 3 | |
| Gene Name | PANK3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 370 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Plays a role in the physiological regulation of the intracellular CoA concentration.. | |
| Protein Sequence | MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Phosphorylation | IKDAKKPSFPWFGMD CCCCCCCCCCCCCEE | 53.47 | 24114839 | |
| 46 | Neddylation | QEEVESLKSIRKYLT HHHHHHHHHHHHHHH | 53.79 | 32015554 | |
| 46 | Ubiquitination | QEEVESLKSIRKYLT HHHHHHHHHHHHHHH | 53.79 | 23000965 | |
| 50 | Ubiquitination | ESLKSIRKYLTSNVA HHHHHHHHHHHCCCC | 42.83 | 23000965 | |
| 71 | Ubiquitination | RDVHLELKDLTLFGR EEEEEEEECCEEEEC | 41.12 | 22817900 | |
| 120 | Ubiquitination | ATGGGAYKFEKDFRT HCCCCCEEECCCCCE | 46.65 | 23503661 | |
| 123 | Ubiquitination | GGAYKFEKDFRTIGN CCCEEECCCCCEECC | 66.36 | 23503661 | |
| 248 | Ubiquitination | GDSTQADKLVRDIYG CCCHHHHHHHHHHHC | 52.47 | 29967540 | |
| 283 | Phosphorylation | IYKEKRESVSKEDLA HHHHHHHCCCHHHHH | 35.41 | 28122231 | |
| 285 | Phosphorylation | KEKRESVSKEDLARA HHHHHCCCHHHHHHH | 39.34 | 28122231 | |
| 286 | Ubiquitination | EKRESVSKEDLARAT HHHHCCCHHHHHHHE | 53.76 | 29967540 | |
| 293 | Phosphorylation | KEDLARATLVTITNN HHHHHHHEEEEECCC | 19.06 | 30622161 | |
| 296 | Phosphorylation | LARATLVTITNNIGS HHHHEEEEECCCHHH | 25.79 | 30622161 | |
| 298 | Phosphorylation | RATLVTITNNIGSVA HHEEEEECCCHHHHH | 16.91 | 30622161 | |
| 303 | Phosphorylation | TITNNIGSVARMCAV EECCCHHHHHHHHHH | 14.60 | 30622161 | |
| 313 | Ubiquitination | RMCAVNEKINRVVFV HHHHHCCCCCEEEEE | 39.83 | 24816145 | |
| 343 | Ubiquitination | YALDYWSKGQLKALF HHHHHCCHHHHHHHH | 36.21 | 21890473 | |
| 347 | Ubiquitination | YWSKGQLKALFLEHE HCCHHHHHHHHHHCC | 34.85 | 22817900 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PANK3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PANK3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PANK3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PANK3_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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