PALM_RAT - dbPTM
PALM_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PALM_RAT
UniProt AC Q920Q0
Protein Name Paralemmin-1
Gene Name Palm
Organism Rattus norvegicus (Rat).
Sequence Length 383
Subcellular Localization Cell membrane
Lipid-anchor
Cytoplasmic side . Cell projection, filopodium membrane
Lipid-anchor. Cell projection, axon . Cell projection, dendrite . Cell projection, dendritic spine . Basolateral cell membrane
Lipid-anchor . Apicolateral cell membr
Protein Description Involved in plasma membrane dynamics and cell process formation. Necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner (By similarity)..
Protein Sequence MEVLATDTVSQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARSLEESITRLEKEIDVLEFGESAPAAPKENSAAPSPIRPHSTSPAKEEQKSETMVNAQQTPLGTPKENRKSTPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRDPLPQGVKVYEDETKVVHAVDGLSENGIQPLSSSEVDELIHKADEVTLSEAGSTTGPAEPRGLAEDVTRTTPSRREITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDTIKAELVVIEDSVTPREPAPLNGSAAELPATKEENQTGPTTTPSDTQDLDMKKPRCRCCSVM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MEVLATDT
-------CCEECCCC		7.88-
83PhosphorylationEDEQKARSLEESITR
HHHHHHHHHHHHHHH		45.0225403869
87PhosphorylationKARSLEESITRLEKE
HHHHHHHHHHHHHHH		21.6428432305
89PhosphorylationRSLEESITRLEKEID
HHHHHHHHHHHHHHC		38.1828432305
112PhosphorylationPAAPKENSAAPSPIR
CCCCCCCCCCCCCCC		27.2227097102
116PhosphorylationKENSAAPSPIRPHST
CCCCCCCCCCCCCCC		28.3827097102
122PhosphorylationPSPIRPHSTSPAKEE
CCCCCCCCCCCCCHH		33.0127097102
123PhosphorylationSPIRPHSTSPAKEEQ
CCCCCCCCCCCCHHH		35.3827097102
124PhosphorylationPIRPHSTSPAKEEQK
CCCCCCCCCCCHHHH		26.3527097102
132PhosphorylationPAKEEQKSETMVNAQ
CCCHHHHCCCCCCCC		37.6827097102
134PhosphorylationKEEQKSETMVNAQQT
CHHHHCCCCCCCCCC		33.2527097102
141PhosphorylationTMVNAQQTPLGTPKE
CCCCCCCCCCCCCCC		14.3823984901
145PhosphorylationAQQTPLGTPKENRKS
CCCCCCCCCCCCCCC		38.5823712012
152PhosphorylationTPKENRKSTPVRSPG
CCCCCCCCCCCCCCC		34.4027097102
153PhosphorylationPKENRKSTPVRSPGG
CCCCCCCCCCCCCCH		28.9230411139
157PhosphorylationRKSTPVRSPGGSTMM
CCCCCCCCCCHHHHH		28.2927097102
161PhosphorylationPVRSPGGSTMMKAAM
CCCCCCHHHHHHEEE		21.0330411139
162PhosphorylationVRSPGGSTMMKAAMY
CCCCCHHHHHHEEEE		25.2628432305
188PhosphorylationTGETRVLSSTTLLPR
CCCEEEEEECCCCCC		23.8428432305
189PhosphorylationGETRVLSSTTLLPRD
CCEEEEEECCCCCCC		22.6528432305
190PhosphorylationETRVLSSTTLLPRDP
CEEEEEECCCCCCCC		20.3528432305
219PhosphorylationVHAVDGLSENGIQPL
EEEECCCCCCCCCCC		34.2530240740
227PhosphorylationENGIQPLSSSEVDEL
CCCCCCCCHHHHHHH		38.2030181290
228PhosphorylationNGIQPLSSSEVDELI
CCCCCCCHHHHHHHH		37.9030181290
242PhosphorylationIHKADEVTLSEAGST
HHHCCEEEECCCCCC		23.6327097102
244PhosphorylationKADEVTLSEAGSTTG
HCCEEEECCCCCCCC		18.9427097102
248PhosphorylationVTLSEAGSTTGPAEP
EEECCCCCCCCCCCC		29.8227097102
249PhosphorylationTLSEAGSTTGPAEPR
EECCCCCCCCCCCCC		34.5527097102
250PhosphorylationLSEAGSTTGPAEPRG
ECCCCCCCCCCCCCC		42.7527097102
263PhosphorylationRGLAEDVTRTTPSRR
CCCCCCCCCCCCCCC		34.3230240740
266PhosphorylationAEDVTRTTPSRREIT
CCCCCCCCCCCCEEC		18.9030240740
268PhosphorylationDVTRTTPSRREITGV
CCCCCCCCCCEECCE		41.7125403869
315UbiquitinationEDEAETKKVLGLQDT
CCHHHHHHHHCCHHE		50.54-
333PhosphorylationELVVIEDSVTPREPA
EEEEEECCCCCCCCC		18.3322108457
335PhosphorylationVVIEDSVTPREPAPL
EEEECCCCCCCCCCC		22.1522108457
345PhosphorylationEPAPLNGSAAELPAT
CCCCCCCCCCCCCCC		24.1927097102
352PhosphorylationSAAELPATKEENQTG
CCCCCCCCCCCCCCC		36.7323984901
358PhosphorylationATKEENQTGPTTTPS
CCCCCCCCCCCCCCC		57.6330240740
361PhosphorylationEENQTGPTTTPSDTQ
CCCCCCCCCCCCCCC		44.6527097102
362PhosphorylationENQTGPTTTPSDTQD
CCCCCCCCCCCCCCC		39.5827097102
363PhosphorylationNQTGPTTTPSDTQDL
CCCCCCCCCCCCCCC		24.2327097102
365PhosphorylationTGPTTTPSDTQDLDM
CCCCCCCCCCCCCCC		51.7227097102
367PhosphorylationPTTTPSDTQDLDMKK
CCCCCCCCCCCCCCC		28.4627097102
377S-palmitoylationLDMKKPRCRCCSVM-
CCCCCCCCCCCCCC-		5.46-
379S-palmitoylationMKKPRCRCCSVM---
CCCCCCCCCCCC---		2.02-
380MethylationKKPRCRCCSVM----
CCCCCCCCCCC----		1.45-
380FarnesylationKKPRCRCCSVM----
CCCCCCCCCCC----		1.45-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PALM_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PALM_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PALM_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PALM_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PALM_RAT

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Related Literatures of Post-Translational Modification

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