| UniProt ID | PAL4A_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y536 | |
| Protein Name | Peptidyl-prolyl cis-trans isomerase A-like 4A {ECO:0000305} | |
| Gene Name | PPIAL4A {ECO:0000312|HGNC:HGNC:24369} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 164 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).. | |
| Protein Sequence | MVNSVVFFDITVDGKPLGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 40 | Phosphorylation | AENFRALSTGEKGFR HHHHHHCCCCCCCCE | 33.12 | 21406692 | |
| 41 | Phosphorylation | ENFRALSTGEKGFRY HHHHHCCCCCCCCEE | 50.65 | 21406692 | |
| 62 | S-nitrosocysteine | RIIPGFMCQGGDFTR CEECCCEEECCCCCC | 2.96 | - | |
| 62 | S-nitrosylation | RIIPGFMCQGGDFTR CEECCCEEECCCCCC | 2.96 | 19483679 | |
| 68 | Phosphorylation | MCQGGDFTRHNGTGD EEECCCCCCCCCCCC | 35.44 | 21712546 | |
| 91 | Acetylation | DDENLIRKHTGSGIL CCCCHHHHHCCCCHH | 38.23 | - | |
| 93 | Phosphorylation | ENLIRKHTGSGILSM CCHHHHHCCCCHHHC | 35.76 | - | |
| 95 | Phosphorylation | LIRKHTGSGILSMAN HHHHHCCCCHHHCCC | 24.66 | - | |
| 99 | Phosphorylation | HTGSGILSMANAGPN HCCCCHHHCCCCCCC | 17.58 | - | |
| 107 | Phosphorylation | MANAGPNTNGSQFFI CCCCCCCCCCCCEEE | 44.05 | 20068231 | |
| 125 | Methylation | KTEWLDGKHVAFGKV ECEEECCCCEEECCH | 34.27 | - | |
| 125 | "N6,N6-dimethyllysine" | KTEWLDGKHVAFGKV ECEEECCCCEEECCH | 34.27 | - | |
| 125 | Sumoylation | KTEWLDGKHVAFGKV ECEEECCCCEEECCH | 34.27 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PAL4A_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PAL4A_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PAL4A_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PAL4A_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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