| UniProt ID | PABP5_ARATH | |
|---|---|---|
| UniProt AC | Q05196 | |
| Protein Name | Polyadenylate-binding protein 5 | |
| Gene Name | PAB5 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 682 | |
| Subcellular Localization | Cytoplasm. Nucleus. | |
| Protein Description | Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.. | |
| Protein Sequence | MAAAVASGIAPTTAMVDQVIPNQPTVAAAAPPPFPAVSQVAAVAAAAAAAEALQTHPNSSLYVGDLDPSVNESHLLDLFNQVAPVHNLRVCRDLTHRSLGYAYVNFANPEDASRAMESLNYAPIRDRPIRIMLSNRDPSTRLSGKGNVFIKNLDASIDNKALYETFSSFGTILSCKVAMDVVGRSKGYGFVQFEKEETAQAAIDKLNGMLLNDKQVFVGHFVRRQDRARSESGAVPSFTNVYVKNLPKEITDDELKKTFGKYGDISSAVVMKDQSGNSRSFGFVNFVSPEAAAVAVEKMNGISLGEDVLYVGRAQKKSDREEELRRKFEQERISRFEKLQGSNLYLKNLDDSVNDEKLKEMFSEYGNVTSCKVMMNSQGLSRGFGFVAYSNPEEALLAMKEMNGKMIGRKPLYVALAQRKEERQAHLQSLFTQIRSPGTMSPVPSPMSGFHHHPPGGPMSGPHHPMFIGHNGQGLVPSQPMGYGYQVQFMPGMRPGAGPPNFMMPFPLQRQTQPGPRVGFRRGANNMQQQFQQQQMLQQNASRFMGGAGNRRNGMEASAPQGIIPLPLNASANSHNAPQRSHKPTPLTISKLASDLALASPDKHPRMLGDHLYPLVEQQEPANAAKVTGMLLEMDQAEILHLLESPEALKAKVSEALDVLRRSADPAAVSSVDDQFALSSSE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 230 | Phosphorylation | RRQDRARSESGAVPS HHHHHHHCCCCCCCC | 34.82 | 19880383 | |
| 232 | Phosphorylation | QDRARSESGAVPSFT HHHHHCCCCCCCCCE | 33.04 | 19880383 | |
| 342 | Phosphorylation | RFEKLQGSNLYLKNL HHHHHHCCCEEECCC | 15.65 | 24894044 | |
| 594 | Phosphorylation | LTISKLASDLALASP CHHHHHHHHHHHCCC | 43.52 | 19880383 | |
| 600 | Phosphorylation | ASDLALASPDKHPRM HHHHHHCCCCCCHHH | 34.19 | 30291188 | |
| 670 | Phosphorylation | SADPAAVSSVDDQFA CCCHHHHCCCCHHHH | 21.66 | 19880383 | |
| 671 | Phosphorylation | ADPAAVSSVDDQFAL CCHHHHCCCCHHHHC | 23.98 | 19880383 | |
| 679 | Phosphorylation | VDDQFALSSSE---- CCHHHHCCCCC---- | 28.52 | 27531888 | |
| 680 | Phosphorylation | DDQFALSSSE----- CHHHHCCCCC----- | 39.06 | 27531888 | |
| 681 | Phosphorylation | DQFALSSSE------ HHHHCCCCC------ | 43.90 | 19880383 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PABP5_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PABP5_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PABP5_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PABP5_ARATH !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Site-specific phosphorylation profiling of Arabidopsis proteins bymass spectrometry and peptide chip analysis."; de la Fuente van Bentem S., Anrather D., Dohnal I., Roitinger E.,Csaszar E., Joore J., Buijnink J., Carreri A., Forzani C.,Lorkovic Z.J., Barta A., Lecourieux D., Verhounig A., Jonak C.,Hirt H.; J. Proteome Res. 7:2458-2470(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-600, AND MASSSPECTROMETRY. | |
