dbPTM

P2Y11_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	P2Y11_HUMAN
UniProt AC	Q96G91
Protein Name	P2Y purinoceptor 11
Gene Name	P2RY11
Organism	Homo sapiens (Human).
Sequence Length	374
Subcellular Localization	Cell membrane Multi-pass membrane protein.
Protein Description	Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP..
Protein Sequence	MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	N-linked_Glycosylation	----MAANVSGAKSC ----CCCCCCCCCCC	20.96	UniProtKB CARBOHYD
54	Phosphorylation	GLALYRFSIRKQRPW CEEEEEEECCCCCCC	16.69	29496963
110	Phosphorylation	RLERFLFTCNLLGSV HHHHHHHHHHHHCCH	11.57	-
179	N-linked_Glycosylation	RPQQGAGNCSVARPE CCCCCCCCCCCCCHH	17.85	UniProtKB CARBOHYD
235	Phosphorylation	LGRAVLRSPGMTVAE HHHHHHHCCCCCHHH	22.96	-
338	Phosphorylation	CCRHCPGYRDSWNPE CCCCCCCCCCCCCHH	9.08	30108239
341	Phosphorylation	HCPGYRDSWNPEDAK CCCCCCCCCCHHHHH	21.54	30108239

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of P2Y11_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of P2Y11_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of P2Y11_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of P2Y11_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of P2Y11_HUMAN

Related Literatures of Post-Translational Modification