dbPTM

P24D4_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	P24D4_ARATH
UniProt AC	Q9FVU0
Protein Name	Transmembrane emp24 domain-containing protein p24delta4
Gene Name	CYB
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	212
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type I membrane protein. Golgi apparatus membrane Single-pass type I membrane protein. Cycles between the endoplasmic reticulum and Golgi via COPI and COPII dependent pathways. Mainly located in endoplasmi
Protein Description	Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Required for trafficking GLL23, a component of the PYK10 complex. May act as a receptor facilitating its packing into COPII carriers and export from the endoplasmic reticulum..
Protein Sequence	MKKKMIPTTILLSALIFSLSPICEAVWLTVPHTGSKCVSEEIQSNVIVLADYLVISEEHSIFPTVSVKVTAPYGTVLHHRENTTNGQFAFTTQESGTYLACFEADAKSHGNKDFSINIDWKTGIAAKDWDSIARKEKIEGVELEFKKLEGAVEAIHENLIYLRNREAEMRIVSEKTNSRVAWYSIMSLGICIVVSGLQILYLKQYFEKKKLI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
82	N-linked_Glycosylation	TVLHHRENTTNGQFA CEEEEEECCCCCEEE	-
165	Methylation	NLIYLRNREAEMRIV HHHHHHCCCEEEEEE	-
170	Methylation	RNREAEMRIVSEKTN HCCCEEEEEEECCCC	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of P24D4_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of P24D4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of P24D4_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of P24D4_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of P24D4_ARATH

Related Literatures of Post-Translational Modification