P210L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: P210L_HUMAN
• UniProt AC: Q5VU65
• Protein Name: Nuclear pore membrane glycoprotein 210-like
• Gene Name: NUP210L
• Organism: Homo sapiens (Human).
• Sequence Length: 1888
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MTGCPASSRRRGFGLFFFLRLHRLLLLFLVLRGTLANKLNVPQVLLPFGREPGRVPFLLEAQRGCYTWHSTHHDAVTVEPLYENGTLCSQKAVLIAESTQPIRLSSIILAREIVTDHELRCDVKVDVINSIEIVSRARELYVDDSPLELMVRALDAEGNTFSSLAGMMFEWSIAQDNESAREELSSKIRILKYSEAEYAPPIYIAEMEKEEKQGDVILVSGIRTGAAVVKVRIHEPFYKKVAAALIRLLVLENIFLIPSHDIYLLVGTYIKYQVAKMVQGRVTEVKFPLEHYILELQDHRVALNGSHSEKVAILDDKTAMVTASQLGQTNLVFVHKNVHMRSVSGLPNCTIYVVEPGFLGFTVQPGNRWSLEVGQVYVITVDVFDKSSTKVYISDNLRITYDFPKEYFEEQLTTVNGSYHIVKALKDGVVVINASLTSIIYQNKDIQPIKFLIKHQQEVKIYFPIMLTPKFLAFPHHPMGMLYRYKVQVEGGSGNFTWTSSNETVVIVTTKGVVTAGQVRGNSTVLARDVQNPFRYGEIKIHVLKLNKMELLPFHADVEIGQIIEIPIAMYHINKETKEAMAFTDCSHLSLDLNMDKQGVFTLLKEGIQRPGPMHCSSTHIAAKSLGHTLVTVSVNECDKYLESSATFAAYEPLKALNPVEVALVTWQSVKEMVFEGGPRPWILEPSRFFLELNAEKTEKIGIAQVWLPSKRKQNQYIYRIQCLDLGEQVLTFRIGNHPGVLNPSPAVEVLQVRFICAHPASMSVTPVYKVPAGAQPCPLPQHNKWLIPVSRLRDTVLELAVFDQHRRKFDNFSSLMLEWKSSNETLAHFEDYKSVEMVAKDDGSGQTRLHGHQILKVHQIKGTVLIGVNFVGYSEKKSPKEISNLPRSVDVELLLVDDVTVVPENATIYNHPDVKETFSLVEGSGYFLVNSSEQGVVTITYMEAESSVELVPLHPGFFTLEVYDLCLAFLGPATAHLRVSDIQELELDLIDKVEIDKTVLVTVRVLGSSKRPFQNKYFRNMELKLQLASAIVTLTPMEQQDEYSENYILRATTIGQTTLVAIAKDKMGRKYTSTPRHIEVFPPFRLLPEKMTLIPMNMMQVMSEGGPQPQSIVHFSISNQTVAVVNRRGQVTGKIVGTAVVHGTIQTVNEDTGKVIVFSQDEVQIEVVQLRAVRILAAATRLITATKMPVYVMGVTSTQTPFSFSNANPGLTFHWSMSKRDVLDLVPRHSEVFLQLPVEHNFAMVVHTKAAGRTSIKVTVHCMNSSSGQFEGNLLELSDEVQILVFEKLQLFYPECQPEQILMPINSQLKLHTNREGAAFVSSRVLKCFPNSSVIEEDGEGLLKAGSIAGTAVLEVTSIEPFGVNQTTITGVQVAPVTYLRVSSQPKLYTAQGRTLSAFPLGMSLTFTVQFYNSIGEKFHTHNTQLYLALNRDDLLHIGPGNKNYTYMAQAVNRGLTLVGLWDRRHPGMADYIPVAVEHAIEPDTKLTFVGDIICFSTHLVSQHGEPGIWMISANNILQTDIVTGVGVARSPGTAMIFHDIPGVVKTYREVVVNASSRLMLSYDLKTYLTNTLNSTVFKLFITTGRNGVNLKGFCTPNQALAITKVLLPATLMLCHVQFSNTLLDIPASKVFQVHSDFSMEKGVYVCIIKVRPQSEELLQALSVADTSVYGWATLVSERSKNGMQRILIPFIPAFYINQSELVLSHKQDIGEIRVLGVDRVLRKLEVISSSPVLVVAGHSHSPLTPGLAIYSVRVVNFTSFQQMASPVFINISCVLTSQSEAVVVRAMKDKLGADHCEDSAILKRFTGSYQILLLTLFAVLASTASIFLAYNAFLNKIQTVPVVYVPTLGTPQPGFFNSTSSPPHFMSLQPPLAQSRLQHWLWSIRH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
84	N-linked_Glycosylation	TVEPLYENGTLCSQK EEEECCCCCCCCCCE	34.88	UniProtKB CARBOHYD
115	Phosphorylation	ILAREIVTDHELRCD HHEEECCCCCCCCCC	36.98	-
130	Phosphorylation	VKVDVINSIEIVSRA CEEEEECCEEHHHCH	15.52	23684312
135	Phosphorylation	INSIEIVSRARELYV ECCEEHHHCHHHEEC	26.36	29396449
145	Phosphorylation	RELYVDDSPLELMVR HHEECCCCCHHHHHH	27.24	21815630
196	Ubiquitination	RILKYSEAEYAPPIY HEHHCCHHHCCCCEE	14.79	22053931
220	Phosphorylation	QGDVILVSGIRTGAA CCCEEEEECCCCCCE	25.67	-
240	Ubiquitination	IHEPFYKKVAAALIR ECCHHHHHHHHHHHH	26.23	-
240	Ubiquitination	IHEPFYKKVAAALIR ECCHHHHHHHHHHHH	26.23	22053931
304	N-linked_Glycosylation	QDHRVALNGSHSEKV CCCEEECCCCCCCCE	39.94	UniProtKB CARBOHYD
348	N-linked_Glycosylation	RSVSGLPNCTIYVVE CCCCCCCCCEEEEEC	40.38	UniProtKB CARBOHYD
435	Phosphorylation	GVVVINASLTSIIYQ CEEEEECCCEEEEEC	27.91	29978859
437	Phosphorylation	VVINASLTSIIYQNK EEEECCCEEEEECCC	18.51	29978859
438	Phosphorylation	VINASLTSIIYQNKD EEECCCEEEEECCCC	16.57	29978859
441	Phosphorylation	ASLTSIIYQNKDIQP CCCEEEEECCCCCCC	12.36	29978859
450	Ubiquitination	NKDIQPIKFLIKHQQ CCCCCCEEEEEECCC	40.58	29967540
495	N-linked_Glycosylation	QVEGGSGNFTWTSSN EEECCCCCEEEECCC	32.64	UniProtKB CARBOHYD
510	Phosphorylation	ETVVIVTTKGVVTAG CEEEEEEECCEEEEC	18.20	-
522	N-linked_Glycosylation	TAGQVRGNSTVLARD EECEECCCCEEEEEE	24.76	UniProtKB CARBOHYD
710	Phosphorylation	IAQVWLPSKRKQNQY EEEEECCCCCCCCCE	42.81	24719451
717	Phosphorylation	SKRKQNQYIYRIQCL CCCCCCCEEEEEEEE	13.89	22817900
719	Phosphorylation	RKQNQYIYRIQCLDL CCCCCEEEEEEEEEC	9.20	22817900
812	N-linked_Glycosylation	QHRRKFDNFSSLMLE HHHHHCCCHHHHEEE	41.66	UniProtKB CARBOHYD
815	Phosphorylation	RKFDNFSSLMLEWKS HHCCCHHHHEEEECC	17.41	-
821	Acetylation	SSLMLEWKSSNETLA HHHEEEECCCCCCEE	34.33	7462093
918	Phosphorylation	NHPDVKETFSLVEGS CCCCHHHHEEEEECC	16.89	-
925	Phosphorylation	TFSLVEGSGYFLVNS HEEEEECCEEEEEEC	19.47	-
931	N-linked_Glycosylation	GSGYFLVNSSEQGVV CCEEEEEECCCCCEE	41.80	UniProtKB CARBOHYD
1053	Phosphorylation	ENYILRATTIGQTTL CCEEEEEEEECCCCE	16.71	-
1054	Phosphorylation	NYILRATTIGQTTLV CEEEEEEEECCCCEE	23.33	-
1059	Phosphorylation	ATTIGQTTLVAIAKD EEEECCCCEEEEEEC	16.02	-
1072	Phosphorylation	KDKMGRKYTSTPRHI ECCCCCCCCCCCCEE	12.45	-
1073	Phosphorylation	DKMGRKYTSTPRHIE CCCCCCCCCCCCEEE	29.20	-
1074	Phosphorylation	KMGRKYTSTPRHIEV CCCCCCCCCCCEEEE	33.07	-
1075	Phosphorylation	MGRKYTSTPRHIEVF CCCCCCCCCCEEEEC	19.28	-
1093	Phosphorylation	RLLPEKMTLIPMNMM CCCCCCCEEEECCHH	32.38	24043423
1104	Phosphorylation	MNMMQVMSEGGPQPQ CCHHHHHCCCCCCCC	33.94	24043423
1112	Phosphorylation	EGGPQPQSIVHFSIS CCCCCCCEEEEEEEC	33.01	24043423
1117	Phosphorylation	PQSIVHFSISNQTVA CCEEEEEEECCCEEE	15.38	24043423
1119	Phosphorylation	SIVHFSISNQTVAVV EEEEEEECCCEEEEE	22.99	24043423
1122	Phosphorylation	HFSISNQTVAVVNRR EEEECCCEEEEEECC	18.06	24043423
1308	Phosphorylation	QILMPINSQLKLHTN HEEEECCCCCEECCC	37.29	25693802
1314	Phosphorylation	NSQLKLHTNREGAAF CCCCEECCCCCCHHE	46.54	-
1445	N-linked_Glycosylation	HIGPGNKNYTYMAQA EECCCCCCHHHHHHH	38.08	UniProtKB CARBOHYD
1446	Phosphorylation	IGPGNKNYTYMAQAV ECCCCCCHHHHHHHH	10.80	-
1486	Phosphorylation	EHAIEPDTKLTFVGD EECCCCCCCCEECCE	38.37	27251275
1730	Phosphorylation	LRKLEVISSSPVLVV HHHEEEECCCCEEEE	29.91	26546556
1731	Phosphorylation	RKLEVISSSPVLVVA HHEEEECCCCEEEEE	27.77	26546556
1746	Phosphorylation	GHSHSPLTPGLAIYS CCCCCCCCCCEEEEE	20.77	26546556
1792	Acetylation	VVRAMKDKLGADHCE HHHHHHHHCCCCCCC	43.21	25038526
1805	Acetylation	CEDSAILKRFTGSYQ CCCCHHHHHHCHHHH	39.08	19816265
1852	Phosphorylation	VYVPTLGTPQPGFFN EEECCCCCCCCCCCC	23.12	26853621
1859	N-linked_Glycosylation	TPQPGFFNSTSSPPH CCCCCCCCCCCCCCC	41.96	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of P210L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of P210L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of P210L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of P210L_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.