OZF_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OZF_HUMAN
• UniProt AC: Q15072
• Protein Name: Zinc finger protein OZF
• Gene Name: ZNF146
• Organism: Homo sapiens (Human).
• Sequence Length: 292
• Subcellular Localization: Nucleus .
• Protein Sequence: MSHLSQQRIYSGENPFACKVCGKVFSHKSNLTEHEHFHTREKPFECNECGKAFSQKQYVIKHQNTHTGEKLFECNECGKSFSQKENLLTHQKIHTGEKPFECKDCGKAFIQKSNLIRHQRTHTGEKPFVCKECGKTFSGKSNLTEHEKIHIGEKPFKCSECGTAFGQKKYLIKHQNIHTGEKPYECNECGKAFSQRTSLIVHVRIHSGDKPYECNVCGKAFSQSSSLTVHVRSHTGEKPYGCNECGKAFSQFSTLALHLRIHTGKKPYQCSECGKAFSQKSHHIRHQKIHTH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	LSQQRIYSGENPFAC CCCCCHHCCCCCHHH	36.94	25159151
19	Ubiquitination	GENPFACKVCGKVFS CCCCHHHHHCCEEEC	36.81	32015554
23	Ubiquitination	FACKVCGKVFSHKSN HHHHHCCEEECCCCC	34.67	29967540
28	Sumoylation	CGKVFSHKSNLTEHE CCEEECCCCCCCCCC	39.58	-
28	Ubiquitination	CGKVFSHKSNLTEHE CCEEECCCCCCCCCC	39.58	29967540
28	Sumoylation	CGKVFSHKSNLTEHE CCEEECCCCCCCCCC	39.58	28112733
42	Ubiquitination	EHFHTREKPFECNEC CCCCCCCCCCCCCCC	52.28	-
51	Sumoylation	FECNECGKAFSQKQY CCCCCCCCCHHHCEE	58.90	-
51	Sumoylation	FECNECGKAFSQKQY CCCCCCCCCHHHCEE	58.90	28112733
56	Sumoylation	CGKAFSQKQYVIKHQ CCCCHHHCEEEEEEC	42.26	-
56	Ubiquitination	CGKAFSQKQYVIKHQ CCCCHHHCEEEEEEC	42.26	33845483
56	Sumoylation	CGKAFSQKQYVIKHQ CCCCHHHCEEEEEEC	42.26	28112733
61	Sumoylation	SQKQYVIKHQNTHTG HHCEEEEEECCCCCC	29.15	-
61	Sumoylation	SQKQYVIKHQNTHTG HHCEEEEEECCCCCC	29.15	-
70	Ubiquitination	QNTHTGEKLFECNEC CCCCCCCEEEEECCC	60.88	32015554
79	Ubiquitination	FECNECGKSFSQKEN EEECCCCCCCCHHHC	61.05	-
84	Sumoylation	CGKSFSQKENLLTHQ CCCCCCHHHCCCCCC	47.58	-
84	Ubiquitination	CGKSFSQKENLLTHQ CCCCCCHHHCCCCCC	47.58	32015554
84	Sumoylation	CGKSFSQKENLLTHQ CCCCCCHHHCCCCCC	47.58	-
92	Ubiquitination	ENLLTHQKIHTGEKP HCCCCCCCCCCCCCC	28.93	29967540
95	Phosphorylation	LTHQKIHTGEKPFEC CCCCCCCCCCCCCCC	50.97	24719451
103	Ubiquitination	GEKPFECKDCGKAFI CCCCCCCCCHHHHHH	49.18	-
107	Ubiquitination	FECKDCGKAFIQKSN CCCCCHHHHHHHHHC	46.59	23000965
112	Sumoylation	CGKAFIQKSNLIRHQ HHHHHHHHHCCCEEC	36.17	-
112	Sumoylation	CGKAFIQKSNLIRHQ HHHHHHHHHCCCEEC	36.17	-
112	Ubiquitination	CGKAFIQKSNLIRHQ HHHHHHHHHCCCEEC	36.17	23000965
121	Phosphorylation	NLIRHQRTHTGEKPF CCCEECCCCCCCCCE	19.74	22210691
123	Phosphorylation	IRHQRTHTGEKPFVC CEECCCCCCCCCEEE	46.56	29214152
126	Sumoylation	QRTHTGEKPFVCKEC CCCCCCCCCEEECCC	45.13	-
126	Sumoylation	QRTHTGEKPFVCKEC CCCCCCCCCEEECCC	45.13	-
126	Ubiquitination	QRTHTGEKPFVCKEC CCCCCCCCCEEECCC	45.13	29967540
126	Acetylation	QRTHTGEKPFVCKEC CCCCCCCCCEEECCC	45.13	26822725
131	Ubiquitination	GEKPFVCKECGKTFS CCCCEEECCCCCCCC	51.22	33845483
135	Acetylation	FVCKECGKTFSGKSN EEECCCCCCCCCCCC	59.04	61273
140	Acetylation	CGKTFSGKSNLTEHE CCCCCCCCCCCCCCC	34.67	70891
140	Sumoylation	CGKTFSGKSNLTEHE CCCCCCCCCCCCCCC	34.67	-
140	Ubiquitination	CGKTFSGKSNLTEHE CCCCCCCCCCCCCCC	34.67	32015554
140	Sumoylation	CGKTFSGKSNLTEHE CCCCCCCCCCCCCCC	34.67	-
148	Ubiquitination	SNLTEHEKIHIGEKP CCCCCCCEEECCCCC	41.30	29967540
157	Sumoylation	HIGEKPFKCSECGTA ECCCCCEECCCCCCC	45.43	-
157	Sumoylation	HIGEKPFKCSECGTA ECCCCCEECCCCCCC	45.43	-
157	Ubiquitination	HIGEKPFKCSECGTA ECCCCCEECCCCCCC	45.43	29967540
169	Sumoylation	GTAFGQKKYLIKHQN CCCCCCEEEEEECCC	37.08	-
169	Ubiquitination	GTAFGQKKYLIKHQN CCCCCCEEEEEECCC	37.08	-
169	Sumoylation	GTAFGQKKYLIKHQN CCCCCCEEEEEECCC	37.08	-
173	Sumoylation	GQKKYLIKHQNIHTG CCEEEEEECCCCCCC	36.22	-
173	Sumoylation	GQKKYLIKHQNIHTG CCEEEEEECCCCCCC	36.22	28112733
173	Ubiquitination	GQKKYLIKHQNIHTG CCEEEEEECCCCCCC	36.22	29967540
179	Phosphorylation	IKHQNIHTGEKPYEC EECCCCCCCCCCCCC	43.15	28152594
182	Ubiquitination	QNIHTGEKPYECNEC CCCCCCCCCCCCCCC	55.00	29967540
184	Phosphorylation	IHTGEKPYECNECGK CCCCCCCCCCCCCCC	44.15	28152594
191	Ubiquitination	YECNECGKAFSQRTS CCCCCCCCHHHCCCE	58.90	-
197	Phosphorylation	GKAFSQRTSLIVHVR CCHHHCCCEEEEEEE	21.90	29214152
198	Phosphorylation	KAFSQRTSLIVHVRI CHHHCCCEEEEEEEE	20.49	29214152
204	Methylation	TSLIVHVRIHSGDKP CEEEEEEEEECCCCC	13.16	-
207	Phosphorylation	IVHVRIHSGDKPYEC EEEEEEECCCCCEEE	46.44	25159151
210	Ubiquitination	VRIHSGDKPYECNVC EEEECCCCCEEECCC	53.69	-
235	Phosphorylation	TVHVRSHTGEKPYGC EEEEEECCCCCCCCC	48.56	29496963
238	Ubiquitination	VRSHTGEKPYGCNEC EEECCCCCCCCCCCC	44.90	-
263	Phosphorylation	ALHLRIHTGKKPYQC HHHHHHHCCCCCEEC	48.61	-
265	Ubiquitination	HLRIHTGKKPYQCSE HHHHHCCCCCEECCH	52.29	-
265	Acetylation	HLRIHTGKKPYQCSE HHHHHCCCCCEECCH	52.29	25953088
266	Ubiquitination	LRIHTGKKPYQCSEC HHHHCCCCCEECCHH	50.75	-
266	Sumoylation	LRIHTGKKPYQCSEC HHHHCCCCCEECCHH	50.75	-
266	Sumoylation	LRIHTGKKPYQCSEC HHHHCCCCCEECCHH	50.75	-
275	Ubiquitination	YQCSECGKAFSQKSH EECCHHHHHHHCCCH	58.90	29967540
275	Acetylation	YQCSECGKAFSQKSH EECCHHHHHHHCCCH	58.90	12432485
280	Sumoylation	CGKAFSQKSHHIRHQ HHHHHHCCCHHHHCC	51.03	-
280	Ubiquitination	CGKAFSQKSHHIRHQ HHHHHHCCCHHHHCC	51.03	29967540
280	Sumoylation	CGKAFSQKSHHIRHQ HHHHHHCCCHHHHCC	51.03	-
280	Acetylation	CGKAFSQKSHHIRHQ HHHHHHCCCHHHHCC	51.03	12432495

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OZF_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OZF_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OZF_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of OZF_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.