dbPTM

OSGP2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OSGP2_DROME
UniProt AC	Q9VWD6
Protein Name	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03179}
Gene Name	CG14231
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	409
Subcellular Localization	Mitochondrion .
Protein Description	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance..
Protein Sequence	MHALRNFAGNGIANVFGCGIRRRLSYVLGIETSCDDTGIAIVDTTGRVIANVLESQQEFHTRYGGIIPPRAQDLHRARIESAYQRCMEAAQLKPDQLTAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAHALQARMEHPEQIGYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRLHILPEYRLWNGGRAIEHAAQLASDPLAYEFPLPLAQQRNCNFSFAGIKNNSFRAIRARERAERTPPDGVISNYGDFCAGLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVMSGGVANNDAIYANIEHLAAQYGCRSFRPSKRYCSDNGVMIAWHGVEQLLQDKEASTRYDYDSIDIQGSAGFAESHEEAVAAAAIKCKWIQPLV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of OSGP2_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OSGP2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of OSGP2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OSGP2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OSGP2_DROME

Related Literatures of Post-Translational Modification