| UniProt ID | OSGI2_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y236 | |
| Protein Name | Oxidative stress-induced growth inhibitor 2 | |
| Gene Name | OSGIN2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 505 | |
| Subcellular Localization | ||
| Protein Description | May be involved in meiosis or the maturation of germ cells.. | |
| Protein Sequence | MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHVVLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDGIA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 57 (in isoform 2) | Phosphorylation | - | 7.84 | 22210691 | |
| 58 (in isoform 2) | Phosphorylation | - | 54.04 | 22210691 | |
| 161 | Ubiquitination | FKDWVSSKRRSLKGD HHHHHHHCCCCCCCC | 44.30 | - | |
| 184 | Ubiquitination | RYYKHYVKVMGLQKN HHHHHHHHHHCCCCC | 21.24 | - | |
| 190 | Ubiquitination | VKVMGLQKNFRENTY HHHHCCCCCCCCCCE | 64.20 | - | |
| 199 | Phosphorylation | FRENTYITSVSRLYR CCCCCEEEEEHHHHC | 16.80 | 30631047 | |
| 200 | Phosphorylation | RENTYITSVSRLYRD CCCCEEEEEHHHHCC | 14.45 | 30631047 | |
| 221 | Ubiquitination | QDRDISTKHLQIEKS CCCCCCCCCEEEECC | 35.21 | 21906983 | |
| 227 | Ubiquitination | TKHLQIEKSNFIKRN CCCEEEECCHHHCCC | 52.94 | - | |
| 348 | Ubiquitination | IFKQLPKKLYPEYHK HHHHCCHHHCHHHHH | 51.84 | - | |
| 385 | Phosphorylation | FPEHRVLSFKSDMKC CCCHHCCCCHHHHHH | 27.98 | 24719451 | |
| 420 | Phosphorylation | IGSHPNLSFLKDQGC CCCCCCCHHHHCCCC | 34.86 | 24719451 | |
| 438 | Phosphorylation | HKSSQPITCKGNPVE CCCCCCEEECCCCEE | 18.17 | 25332170 | |
| 475 | Ubiquitination | DNFVRFLKGGALGVT HHHHHHHHCCHHHHH | 53.22 | - | |
| 482 | Phosphorylation | KGGALGVTRCLATRQ HCCHHHHHHHHHHHH | 17.54 | - | |
| 519 (in isoform 2) | Ubiquitination | - | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of OSGI2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of OSGI2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of OSGI2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of OSGI2_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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