dbPTM

ORD_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ORD_DROME
UniProt AC	Q24434
Protein Name	Protein ORD
Gene Name	ord
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	479
Subcellular Localization	Nucleus. Chromosome. Chromosome, centromere. In male meiosis it assembles onto chromosomes in late G2 of the meiotic cell cycle. It remains at the centromeres after chromosome condensation, through the meiosis I division until the separation of siste
Protein Description	Essential for proper maintenance of sister-chromatid cohesion in both male and female meiosis. Mutations in ord cause premature separation of the sister chromatids in meiosis I and random segregation in both meiotic divisions. Required for chiasma maintenance in female meiosis. Mutations in ord reduce recombination in female meiosis..
Protein Sequence	MYGETTLNKNHVIKFIKLKINNCLGCDEVEINFSKADNVHIIIYSLVTDMAKDLPAVTPVAQAILLLCSLTYPDSDSLETIPQLKIGKGSVSMSFKVYPVNKEEETEPESESDLDEGPSTSKQALERMVQRAERKAKEASTRNVHSKGIYVNVERRFDMYFALDTVSYYINGGKRQSCPLPEFHAKFFVRPQHSINLLRQLHEKCSGNWLKVIQSDGDGDAFKKFKDPDSPFETFVKLFESNPIKPNDMMGKLAKTCLHVNEAVRLTEREFILEVFNQVRHIFEYITAQEYTVWFLVPCLGDKDQLRSKTLEDFDLTKVRTSIRRAGDTSNIWWDHTDHNIKDILLVAFQLDLATHVNQSVLVISHLETLAEFSTMQYVTAFFMNDFYAKKNTEPKWICHRYLERIIDVALFLGVIVIIEYPSAFTLLQEGRHLIKCFQKENADSSRTSQWEIFEDVVKENESDLEFLKEAVGKVQQNV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ORD_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ORD_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ORD_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ORD_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
RING1_DROME	Sce	physical	14669021

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ORD_DROME

Related Literatures of Post-Translational Modification