OR4S2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OR4S2_HUMAN
• UniProt AC: Q8NH73
• Protein Name: Olfactory receptor 4S2
• Gene Name: OR4S2
• Organism: Homo sapiens (Human).
• Sequence Length: 311
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Odorant receptor..
• Protein Sequence: MEKINNVTEFIFWGLSQSPEIEKVCFVVFSFFYIIILLGNLLIMLTVCLSNLFKSPMYFFLSFLSFVDICYSSVTAPKMIVDLLAKDKTISYVGCMLQLFGVHFFGCTEIFILTVMAYDRYVAICKPLHYMTIMNRETCNKMLLGTWVGGFLHSIIQVALVVQLPFCGPNEIDHYFCDVHPVLKLACTETYIVGVVVTANSGTIALGSFVILLISYSIILVSLRKQSAEGRRKALSTCGSHIAMVVIFFGPCTFMYMRPDTTFSEDKMVAVFYTIITPMLNPLIYTLRNAEVKNAMKKLWGRNVFLEAKGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	N-linked_Glycosylation	--MEKINNVTEFIFW --CCCCCCCHHHHHH	45.63	UniProtKB CARBOHYD
222	Phosphorylation	SYSIILVSLRKQSAE HHHHHHHHHHHCCHH	21.00	24719451
227	Phosphorylation	LVSLRKQSAEGRRKA HHHHHHCCHHHHHHH	31.18	17924679
286	Phosphorylation	MLNPLIYTLRNAEVK HHHHHHHHHHHHHHH	16.55	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OR4S2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OR4S2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OR4S2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of OR4S2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-227, AND MASSSPECTROMETRY.
PubMed: 17924679