dbPTM

OPLA_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OPLA_ARATH
UniProt AC	Q9FIZ7
Protein Name	5-oxoprolinase
Gene Name	OXP1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1266
Subcellular Localization	Cytoplasm .
Protein Description	Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway..
Protein Sequence	MGTVIEGKLRFCIDRGGTFTDVYAEIPGHSDGHVLKLLSVDPSNYDDAPVEGIRRILEEYTGKKIPRTSKIPTDKIQWIRMGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPDIFDLTVAKPSNLYEEVIEVDERVVLALEDDDDDEGSLIKGVSGEFLRVVKPFDGEGLKPLLKGLLDKGISCLAVVLMHSYTYPKHEMDVEKLALEMGFRHVSLSSALTPMVRAVPRGLTATVDAYLTPVIKEYLSGFISKFDDDLGKVNVLFMQSDGGLAPESRFSGHKAVLSGPAGGVVGYSQTLFGLETEKPLIGFDMGGTSTDVSRYDGSYEQVIETQIAGTIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPDSVGAHPGPVCYRKGGELAVTDANLVLGFVIPDYFPSIFGPNEDQPLDVAATREAFEKLAGQINIYRKSQDPSAKDMSVEEIAMGFVSVANETMCRPIRQLTEMKGHETKNHALACFGGAGPQHACAIARSLGMKEVLVHRYCGILSAYGMGLADVIEDAQEPYSAVYGPESLSEVFRRETVLLREVREKLQEQGFGDGNISTETYLNLRYDGTDTAIMVKGKKTGDGSAFDYAAEFLKLFEQEYGFKLQNRNLLICDVRVRGIGVTSILKPRAVEAAPVTPKVERHYKVYFEGGWHDTPLFKLENLGFGHEILGPAIIMNGNSTVIVEPQCKAIITKYGNIKIEVEPATSSVKLAENVADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFSPDGGLVANAPHVPVHLGAMSSTVRWQLKHWGENLNEGDVLVTNHPCAGGSHLPDITVITPVFDKGKLVFFVASRGHHAEVGGITPGSMPPFSKAIWEEGAAIKAFKVVEKGVFQEEGIVKLLQFPSSDETTTKIPGTRRIQDNLSDLQAQIAANQRGISLIKELIEQYGLGTVQAYMKYVQLNAEEAVREMLKSVANRVSSETPNSRVGNSVTIEEEDYMDDGSIIHLKLTIDADKGEASFDFTGTSPEVYGNWNAPEAVTSAAVIYCLRCLVNVDIPLNQGCLAPVEIRIPAGSFLSPSEKAAVVGGNVLTSQRVTDVVLTAFQACACSQGCMNNLTFGDDTFGYYETIGGGCGAGPTWNGTSGVQCHMTNTRMTDPEIFEQRYPVLLHRFGLRENSGGNGLHKGGDGLVREIEFRKPVVVSILSERRVHSPRGLNGGQNGLRGANYLITKDKRRIYLGGKNTVHVEAGEILQILTPGGGGFGSNI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
155	Phosphorylation	DDDDDEGSLIKGVSG CCCCCCCCEEEECCC	25.52	23111157
656	Phosphorylation	AVEAAPVTPKVERHY EEEECCCCCCCEEEE	19.14	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OPLA_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of OPLA_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OPLA_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of OPLA_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OPLA_ARATH

Related Literatures of Post-Translational Modification