OLIG1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OLIG1_HUMAN
• UniProt AC: Q8TAK6
• Protein Name: Oligodendrocyte transcription factor 1
• Gene Name: OLIG1
• Organism: Homo sapiens (Human).
• Sequence Length: 271
• Subcellular Localization: Nucleus .
• Protein Description: Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity)..
• Protein Sequence: MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MYYAVSQARV -----CCEECCCHHH	10.14	28331001
38	Phosphorylation	SLYELVGYRQPPSSS CHHHHHCCCCCCCCC	9.90	24275569
43	Phosphorylation	VGYRQPPSSSSSSTS HCCCCCCCCCCCCCC	49.92	-
44	Phosphorylation	GYRQPPSSSSSSTSS CCCCCCCCCCCCCCC	39.76	-
45	Phosphorylation	YRQPPSSSSSSTSST CCCCCCCCCCCCCCC	38.28	24275569
46	Phosphorylation	RQPPSSSSSSTSSTS CCCCCCCCCCCCCCC	30.20	24275569
47	Phosphorylation	QPPSSSSSSTSSTSS CCCCCCCCCCCCCCC	39.31	24275569
48	Phosphorylation	PPSSSSSSTSSTSST CCCCCCCCCCCCCCC	33.97	24275569
49	Phosphorylation	PSSSSSSTSSTSSTS CCCCCCCCCCCCCCC	28.75	24275569
50	Phosphorylation	SSSSSSTSSTSSTSS CCCCCCCCCCCCCCC	33.30	24275569
51	Phosphorylation	SSSSSTSSTSSTSSS CCCCCCCCCCCCCCC	32.18	-
52	Phosphorylation	SSSSTSSTSSTSSSS CCCCCCCCCCCCCCC	26.85	-
58	Phosphorylation	STSSTSSSSTTAPLL CCCCCCCCCCCCCCC	31.32	-
86	Phosphorylation	PPGPGPGSGAHPGGS CCCCCCCCCCCCCCC	35.62	-
93	Phosphorylation	SGAHPGGSARPDAKE CCCCCCCCCCCCHHH	27.33	-
153	Phosphorylation	RKLSKIATLLLARNY CHHHHHHHHHHHHHH	22.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OLIG1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OLIG1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OLIG1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PSDE_HUMAN	PSMD14	physical	21988832
GRB7_HUMAN	GRB7	physical	25814554
HCK_HUMAN	HCK	physical	25814554
P55G_HUMAN	PIK3R3	physical	25814554
YES_HUMAN	YES1	physical	25814554

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.