OLA1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OLA1_MOUSE
• UniProt AC: Q9CZ30
• Protein Name: Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}
• Gene Name: Ola1
• Organism: Mus musculus (Mouse).
• Sequence Length: 396
• Subcellular Localization: Cytoplasm . Nucleus . Nucleus, nucleolus . Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm.
• Protein Description: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP..
• Protein Sequence: MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPILDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKDEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Malonylation	---MPPKKGGDGIKP ---CCCCCCCCCCCC	74.11	26320211
11	Ubiquitination	KKGGDGIKPPPIIGR CCCCCCCCCCCCCCC	57.93	27667366
55	Glutathionylation	SAENFPFCTIDPNES HHCCCCCEEECCCCC	3.12	24333276
79	Acetylation	DFLCQYHKPASKIPA CHHHHCCCCHHHCCH	37.03	22826441
83	Ubiquitination	QYHKPASKIPAFLNV HCCCCHHHCCHHHCH	55.61	-
166	Acetylation	MIGPILDKLEKVAVR HHHHHHHHHHHHHCC	55.91	23954790
166	Ubiquitination	MIGPILDKLEKVAVR HHHHHHHHHHHHHCC	55.91	-
169	Malonylation	PILDKLEKVAVRGGD HHHHHHHHHHCCCCC	46.03	26320211
187	S-nitrosocysteine	KPEYDIMCKVKSWVI CCCCEEEEEEEEEEE	4.72	-
187	S-nitrosylation	KPEYDIMCKVKSWVI CCCCEEEEEEEEEEE	4.72	21278135
187	Glutathionylation	KPEYDIMCKVKSWVI CCCCEEEEEEEEEEE	4.72	24333276
190	Ubiquitination	YDIMCKVKSWVIDQK CEEEEEEEEEEECCC	24.89	27667366
191	Phosphorylation	DIMCKVKSWVIDQKK EEEEEEEEEEECCCC	29.57	-
209	Acetylation	FYHDWNDKEIEVLNK EEECCCHHHHHHHHH	58.33	23954790
216	Acetylation	KEIEVLNKHLFLTSK HHHHHHHHHEEECCC	37.21	23236377
234	Acetylation	YLVNLSEKDYIRKKN EEEECCHHHHHHHCC	53.08	23954790
253	Acetylation	KIKEWVDKYDPGALV EHHHHHHHCCCCCEE	41.77	23954790
281	Ubiquitination	LSAEERQKYLEANMT CCHHHHHHHHHHHCC	59.01	-
282	Phosphorylation	SAEERQKYLEANMTQ CHHHHHHHHHHHCCH	11.05	28059163
290	Phosphorylation	LEANMTQSALPKIIK HHHHCCHHHHHHHHH	23.70	28059163
294	Malonylation	MTQSALPKIIKAGFA CCHHHHHHHHHHHHH	58.89	26320211
294	Acetylation	MTQSALPKIIKAGFA CCHHHHHHHHHHHHH	58.89	22826441
340	Acetylation	KIHTDFEKGFIMAEV CCCCCHHHCCEEEEE	60.14	22826441
354	Acetylation	VMKYEDFKDEGSENA EEEHHHHCCCCCHHH	68.16	23954790
394	Malonylation	FNTPQQPKKK----- ECCCCCCCCC-----	69.71	26320211
394	Ubiquitination	FNTPQQPKKK----- ECCCCCCCCC-----	69.71	27667366

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OLA1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OLA1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OLA1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of OLA1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.