OGFD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OGFD2_HUMAN
• UniProt AC: Q6N063
• Protein Name: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
• Gene Name: OGFOD2
• Organism: Homo sapiens (Human).
• Sequence Length: 350
• Protein Sequence: MATVGAPRHFCRCACFCTDNLYVARYGLHVRFRGEQQLRRDYGPILRSRGCVSAKDFQQLLAELEQEVERRQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYSVSPDADLKGLLQRLETVSEEKRIYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMNNYGVLLHELGLDEPLMTPLRERFLQPLMALLYPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAELTLNVALGKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRGGQLHGARPLGTGERWNLVVWLRASAVRNSLCPMCCREPDLVDDEGFGDGFTREEPATVDVCALT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
42	Phosphorylation	EQQLRRDYGPILRSR CCHHHHHCCHHHHCC	24.00	28258704
53	Phosphorylation	LRSRGCVSAKDFQQL HHCCCCCCHHHHHHH	33.41	28258704
77 (in isoform 2)	Ubiquitination	-	40.31	21906983
82	Ubiquitination	GQESAARKALIASSY CCHHHHHHHHHHHCC	42.70	-
113	Phosphorylation	APEFLAVTEYSVSPD CHHHEEEEEEECCCC	24.49	22468782
115	Phosphorylation	EFLAVTEYSVSPDAD HHEEEEEEECCCCCC	12.66	22468782
124	Ubiquitination	VSPDADLKGLLQRLE CCCCCCHHHHHHHHH	48.32	-
132	Phosphorylation	GLLQRLETVSEEKRI HHHHHHHHCCCCCCE	33.64	22210691
137	Ubiquitination	LETVSEEKRIYRVPV HHHCCCCCCEEECCC	39.79	2190698
137 (in isoform 1)	Ubiquitination	-	39.79	21906983
140	Phosphorylation	VSEEKRIYRVPVFTA CCCCCCEEECCCCHH	15.02	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OGFD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OGFD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OGFD2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1G_HUMAN	EEF1G	physical	16169070
KAT5_HUMAN	KAT5	physical	16169070

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• DB00126: Vitamin C