ODO2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ODO2_SCHPO
• UniProt AC: O94681
• Protein Name: Probable dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
• Gene Name: kgd2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 452
• Subcellular Localization: Mitochondrion.
• Protein Description: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)..
• Protein Sequence: MTSYGNGFRMMAKCLLSLRSGYSVTAPVSKSMANVLWARYASTRIKTPPFPESITEGTLAQWLKQPGEYVNKDEEIASVETDKIDAPVTAPDAGVLKEQLVKEGDTITIDQDIAVIDTSAAPPEGGSAGPKKDEVKTADADAAKDLSTPQDSSKPIEEKPMPDLGAEQKESAPSSTKPAPDAKEPEFSSPKPKPAKSEPVKQSKPKATETARPSSFSRNEDRVKMNRMRLRIAERLKESQNRAASLTTFNECDMSAVVALRKKYKDEILKETGVKIGFMSFFSKACTQAMKQIPAINGSIEGEGKGDTLVYRDFCDLSIAVATPKGLVTPVIRNAESMSLLEIESAIATLGSKARAGKLAIEDMASGTFTISNGGIFGSLYGTPIINLPQTAVLGLHAIKERPVVINGQVVPRPMMYLALTYDHRMVDGREAVTFLRLVKEYIEDPAKMLLV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTSYGNGFR ------CCCCCHHHH	30.56	21712547
4	Phosphorylation	----MTSYGNGFRMM ----CCCCCHHHHHH	12.87	21712547
23	Phosphorylation	LSLRSGYSVTAPVSK HHCCCCCEEEECCCH	19.27	21712547
83	N6-lipoyllysine	IASVETDKIDAPVTA CEEEECCCCCCCCCC	50.32	-
83	Lipoylation	IASVETDKIDAPVTA CEEEECCCCCCCCCC	50.32	-
83	Lipoylation	IASVETDKIDAPVTA CEEEECCCCCCCCCC	50.32	-
214	Phosphorylation	ATETARPSSFSRNED CCCCCCCCCCCCCHH	38.16	29996109
215	Phosphorylation	TETARPSSFSRNEDR CCCCCCCCCCCCHHH	29.89	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ODO2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ODO2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ODO2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of ODO2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.