dbPTM

NXPH4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NXPH4_HUMAN
UniProt AC	O95158
Protein Name	Neurexophilin-4
Gene Name	NXPH4
Organism	Homo sapiens (Human).
Sequence Length	308
Subcellular Localization	Secreted .
Protein Description	May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors..
Protein Sequence	MRLLPEWFLLLFGPWLLRKAVSAQIPESGRPQYLGLRPAAAGAGAPGQQLPEPRSSDGLGVGRAWSWAWPTNHTGALARAGAAGALPAQRTKRKPSIKAARAKKIFGWGDFYFRVHTLKFSLLVTGKIVDHVNGTFSVYFRHNSSSLGNLSVSIVPPSKRVEFGGVWLPGPVPHPLQSTLALEGVLPGLGPPLGMAAAAAGPGLGGSLGGALAGPLGGALGVPGAKESRAFNCHVEYEKTNRARKHRPCLYDPSQVCFTEHTQSQAAWLCAKPFKVICIFVSFLSFDYKLVQKVCPDYNFQSEHPYFG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Acetylation	FGPWLLRKAVSAQIP HHHHHHHHHHHCCCC	53.78	25953088
72	N-linked_Glycosylation	WSWAWPTNHTGALAR EECCCCCCCHHHHHH	27.00	UniProtKB CARBOHYD
133	N-linked_Glycosylation	GKIVDHVNGTFSVYF CEEEECCCCEEEEEE	40.13	UniProtKB CARBOHYD
143	N-linked_Glycosylation	FSVYFRHNSSSLGNL EEEEEECCCCCCCEE	39.05	UniProtKB CARBOHYD
149	N-linked_Glycosylation	HNSSSLGNLSVSIVP CCCCCCCEEEEEEEC	34.14	UniProtKB CARBOHYD
293	Ubiquitination	FDYKLVQKVCPDYNF CCHHHHHHHCCCCCC	38.02	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NXPH4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NXPH4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NXPH4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NXPH4_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NXPH4_HUMAN

Related Literatures of Post-Translational Modification