NXNL1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NXNL1_HUMAN
• UniProt AC: Q96CM4
• Protein Name: Nucleoredoxin-like protein 1
• Gene Name: NXNL1
• Organism: Homo sapiens (Human).
• Sequence Length: 212
• Subcellular Localization: Nucleus outer membrane.
• Protein Description: May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods..
• Protein Sequence: MASLFSGRILIRNNSDQDELDTEAEVSRRLENRLVLLFFGAGACPQCQAFVPILKDFFVRLTDEFYVLRAAQLALVYVSQDSTEEQQDLFLKDMPKKWLFLPFEDDLRRDLGRQFSVERLPAVVVLKPDGDVLTRDGADEIQRLGTACFANWQEAAEVLDRNFQLPEDLEDQEPRSLTECLRRHKYRVEKAARGGRDPGGGGGEEGGAGGLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MASLFSGRILIRN --CCCCCCCCEEEEC	32.24	24719451
185	Acetylation	TECLRRHKYRVEKAA HHHHHHHHHHHHHHH	32.70	7307383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NXNL1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NXNL1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NXNL1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of NXNL1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.