NUP88_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NUP88_ARATH
• UniProt AC: Q9FFK6
• Protein Name: Nuclear pore complex protein NUP88 {ECO:0000303|PubMed:21189294}
• Gene Name: NUP88 {ECO:0000303|PubMed:21189294}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 810
• Subcellular Localization: Nucleus envelope . Nucleus, nuclear pore complex .
• Protein Description: Involved in the regulation of exportin-mediated nuclear protein export. Required for resistance mediated by multiple R proteins and for the appropriate nuclear accumulation of SNC1 and of the downstream defense signaling components EDS1 and NPR1. Not involved in salt tolerance, ethylene and auxin responses, but required for systemic acquired resistance..
• Protein Sequence: MKFNFNETEDAPDSRRSPTPKEPVRWVPLQSHPVFASLPSSQDEPAVSQLFPRNFMAWDGDSRVYYWDSRRYLLHRLSLRLGEPEPSSVLAAVPSKVMQPDLQVTFSVSKISINKSGSAVLLAGSDGICVMYLFGRASVIEDNVICRVVSIGSEIYTSSDSAITLLQASWHPDSDTHLGILSSDAVFRLFDLSSDTELPEQEYYLQPGEPGRSRTASSIYPADFSFGGDHLWDRFTVFILFTDGSIYILCPVVPFGSVYKWESVMEIYNDANMYGVKSSNSLAVSNSSLAIEWLEATFPDLTEQGTRGENILVVKAQPYALLDASLALQGPLYKASSGDGDEDFAVREAECKGRAVSLLYNLVSKDSILVTAWSAGQLQVDALVDEIQPVWISGNSSRLRMNSHNKIQGVAMICESNISELPVATSNLPLDHTVWLGHPPPLLRLAMVDLALPKMREGGSLVTLFADSLLPERIYSLHDGGIDSTVLHSLPFTSQASGKDEALKTPSVHTVLSTCQEESAVSPLLGFVPLSDSFGYSWIVAVLSSGECIVAEMKTWDLLLPIHVSTDKTVSSSAIEKKEQENSCIISKELLAGPKIRIAPHALPNQRSTPANSVEGRSILLDYVKLFHENYIEYAHKVHFELQHHAPNLKRIIDDQHQRLAEANEKISKVEKNQSFLEKRIDKAIERHDSLEQCLQRLRSLPGTHKKPLTRAELDFKSELDQYAGVEVDALQSSIETLRARVKKSTQKSHKGTVVAASQKKQYSKKNLIQDTQMSQLQSTLAKLSLMNSDNSKKVKIVESALKSQESSFM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
319	Phosphorylation	LVVKAQPYALLDASL EEEECCCCHHHCHHH		26811356
325	Phosphorylation	PYALLDASLALQGPL CCHHHCHHHHHCCCE		26811356
623	Phosphorylation	GRSILLDYVKLFHEN CHHHHHHHHHHHHHH		19880383
749	Phosphorylation	VKKSTQKSHKGTVVA HHHHCCCCCCCEEEE		22074104
758	Phosphorylation	KGTVVAASQKKQYSK CCEEEEHHHCHHHCC		22074104
780	Phosphorylation	QMSQLQSTLAKLSLM HHHHHHHHHHHHHHH		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NUP88_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NUP88_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NUP88_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.