dbPTM

NUP44_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NUP44_SCHPO
UniProt AC	O42963
Protein Name	Nucleoporin nup44
Gene Name	nup44
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	403
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope..
Protein Sequence	MAFSFGQQGSSIKAPSIGSTGVFGQSNTTKPTAPFGSGSIFGSTNTNVGAGGPTGSSSAPPFGNSIFGKTQQQPTTSFSNTTTNAPQSTVFGQNAASRTGNSNTQPLFSWSTVNNPTKPVDETNATIPSSLLLSSGISPNATVSNAQYGPAQPPSVEEQVQKILNAWNLNHPDCAFQRFFYNKVPVEQAALYVKPPNYNQQKWDEAVANRPSNSVVPVLAVGFPDVQKRINMQIQQVNTYRIRMREIVETLGRLSNKHDLDFSIKLAEAKNRHVRLSERILRLAIKVHVLRHRGYALKPNEEELRKKLDDLTKSLNNPEIFGRLNEIWARITLIFEGEKISEDQRSNLAKGVVDWRKNSDQLEVITDVLRDHQVGLSYVVKLMQEDLATLNKQLTEHVPQSQK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
314	Phosphorylation	KLDDLTKSLNNPEIF HHHHHHHHHCCHHHH	30.97	25720772
359	Phosphorylation	VVDWRKNSDQLEVIT CCCHHHCCHHHHHHH	29.75	25720772
401	Phosphorylation	LTEHVPQSQK----- HHHHCCCCCC-----	33.59	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NUP44_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NUP44_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NUP44_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NUP44_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NUP44_SCHPO

Related Literatures of Post-Translational Modification