NUFP2_MOUSE - dbPTM
NUFP2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NUFP2_MOUSE
UniProt AC Q5F2E7
Protein Name Nuclear fragile X mental retardation-interacting protein 2
Gene Name Nufip2
Organism Mus musculus (Mouse).
Sequence Length 692
Subcellular Localization Nucleus . Cytoplasm . Cytoplasm, Stress granule . Localized in both nucleus and cytoplasm in most neurons. In the cortex, distributed in a diffuse way in the nucleus and in the cytoplasm. Localized in the cytoplasm in neurons of the dentate gyrus in
Protein Description Binds RNA..
Protein Sequence MEEKPGQPQPQHHHSHHHPHHHPQQQQQQQSHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGEINGNAGEREISLKSLSSDEATNPISRVLNGNQQVVETSLKQTVKTSTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGETQAVDKTDTIAIPNGVITSSSGYITNGYMSKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNLVQDKIMQETSVPALKQGLETLKPDYSEQKGMRVDGSKPIWKYETGPGGTSRGKPAMGDVLRKSSDIKPGLSSKKFDDRPKGKHASAAASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKTVQNSSVSPSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSASFSNGPVLAGTDGSVYPSGGQPLLTTAANTLTPISTGTDSVLQDMSLASAAVEQIKSSLFIYPSNMQTVLLSAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVIGKSSDHKVMEVTFQGEYPATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGHILKPGTTESGALSLDPSHIGDLQKADTSSQGALVFLSKDYEIENQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEMESIWNLQKQDPKRIITYNEAMDSPDQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
88PhosphorylationTLQQHQETPKKKTGY
HHHHHCCCCCCCCCC		33.5625266776
95PhosphorylationTPKKKTGYGEINGNA
CCCCCCCCCCCCCCC		19.4772115
111PhosphorylationEREISLKSLSSDEAT
CEEEEEEECCCCCCC		38.4827087446
113PhosphorylationEISLKSLSSDEATNP
EEEEEECCCCCCCCH		42.7227087446
114PhosphorylationISLKSLSSDEATNPI
EEEEECCCCCCCCHH		44.7722942356
118PhosphorylationSLSSDEATNPISRVL
ECCCCCCCCHHHHHH		39.2125619855
135PhosphorylationNQQVVETSLKQTVKT
CHHEEEEEHHHHHCC		21.7726026062
147UbiquitinationVKTSTFGKAGIKTKN
HCCCCCCCCCCCCCC		38.9727667366
160PhosphorylationKNFIQKNSMDKKNGK
CCCHHHCCCCCCCCC		35.0829514104
213PhosphorylationKGADNDGSGSESGYT
CCCCCCCCCCCCCCC		41.8527087446
215PhosphorylationADNDGSGSESGYTTP
CCCCCCCCCCCCCCH		30.2225521595
217PhosphorylationNDGSGSESGYTTPKK
CCCCCCCCCCCCHHH		38.506458829
219PhosphorylationGSGSESGYTTPKKRK
CCCCCCCCCCHHHHH		19.4023684622
220PhosphorylationSGSESGYTTPKKRKA
CCCCCCCCCHHHHHH		39.9025521595
221PhosphorylationGSESGYTTPKKRKAR
CCCCCCCCHHHHHHH		25.3225521595
231PhosphorylationKRKARRNSAKGCENL
HHHHHHHCCCCCCCH		29.5522942356
282PhosphorylationGSKPIWKYETGPGGT
CCCCCEEEECCCCCC		12.0620531401
284PhosphorylationKPIWKYETGPGGTSR
CCCEEEECCCCCCCC		45.6620531401
290PhosphorylationETGPGGTSRGKPAMG
ECCCCCCCCCCCCCH		42.1620531401
291MethylationTGPGGTSRGKPAMGD
CCCCCCCCCCCCCHH		57.92-
293AcetylationPGGTSRGKPAMGDVL
CCCCCCCCCCCHHHH		28.6119849209
303PhosphorylationMGDVLRKSSDIKPGL
CHHHHHHCCCCCCCC		27.1529895711
304PhosphorylationGDVLRKSSDIKPGLS
HHHHHHCCCCCCCCC		46.5228507225
311PhosphorylationSDIKPGLSSKKFDDR
CCCCCCCCCCCCCCC		46.1322418434
312PhosphorylationDIKPGLSSKKFDDRP
CCCCCCCCCCCCCCC		44.9322418434
369PhosphorylationVKENLNKTVQNSSVS
HHHHHHHHHHCCCCC		26.6726643407
373PhosphorylationLNKTVQNSSVSPSSS
HHHHHHCCCCCCCCC		18.2826643407
374PhosphorylationNKTVQNSSVSPSSSS
HHHHHCCCCCCCCCC		33.8826643407
376PhosphorylationTVQNSSVSPSSSSSS
HHHCCCCCCCCCCCC		22.4724453211
378PhosphorylationQNSSVSPSSSSSSSS
HCCCCCCCCCCCCCC		35.0326643407
379PhosphorylationNSSVSPSSSSSSSST
CCCCCCCCCCCCCCC		37.3123140645
380PhosphorylationSSVSPSSSSSSSSTG
CCCCCCCCCCCCCCC		38.2823140645
381PhosphorylationSVSPSSSSSSSSTGE
CCCCCCCCCCCCCCC		35.8723140645
382PhosphorylationVSPSSSSSSSSTGET
CCCCCCCCCCCCCCC		35.8723140645
383PhosphorylationSPSSSSSSSSTGETQ
CCCCCCCCCCCCCCC		30.2023140645
384PhosphorylationPSSSSSSSSTGETQT
CCCCCCCCCCCCCCC		33.5923140645
385PhosphorylationSSSSSSSSTGETQTQ
CCCCCCCCCCCCCCC		42.2423140645
386PhosphorylationSSSSSSSTGETQTQS
CCCCCCCCCCCCCCC		40.7723140645
403PhosphorylationRLSQVPMSALKSVTS
HHHHCCHHHHHHHHC		25.1229514104
569PhosphorylationAYELEKRTSPQVLGH
HHHCCCCCCCCHHCE		56.6926824392
570PhosphorylationYELEKRTSPQVLGHI
HHCCCCCCCCHHCEE		19.8526824392
582PhosphorylationGHILKPGTTESGALS
CEECCCCCCCCCCCC		35.6025777480
583PhosphorylationHILKPGTTESGALSL
EECCCCCCCCCCCCC		33.7825777480
585PhosphorylationLKPGTTESGALSLDP
CCCCCCCCCCCCCCH		27.5525777480
589PhosphorylationTTESGALSLDPSHIG
CCCCCCCCCCHHHHC		30.1425777480
593PhosphorylationGALSLDPSHIGDLQK
CCCCCCHHHHCCHHH		27.6625777480
603PhosphorylationGDLQKADTSSQGALV
CCHHHCCCCCCCEEE		34.8323984901
604PhosphorylationDLQKADTSSQGALVF
CHHHCCCCCCCEEEE		22.6326643407
605PhosphorylationLQKADTSSQGALVFL
HHHCCCCCCCEEEEE		34.4229514104
613PhosphorylationQGALVFLSKDYEIEN
CCEEEEECCCCEECC		16.4130635358
616PhosphorylationLVFLSKDYEIENQNP
EEEECCCCEECCCCC		23.6525619855
626PhosphorylationENQNPLASPTNTLLG
CCCCCCCCCCCHHHC		39.6824925903
628PhosphorylationQNPLASPTNTLLGSA
CCCCCCCCCHHHCCH		38.0425521595
630PhosphorylationPLASPTNTLLGSAKE
CCCCCCCHHHCCHHH		26.3224925903
634PhosphorylationPTNTLLGSAKEQRYQ
CCCHHHCCHHHHHHH		35.8224925903
649PhosphorylationRGLERNDSWGSFDLR
HHCCCCCCCCCCHHH		36.5618388127
652PhosphorylationERNDSWGSFDLRAAI
CCCCCCCCCHHHHHE		14.8821082442
682PhosphorylationQDPKRIITYNEAMDS
CCCCCEEECHHHCCC		20.2325619855
683PhosphorylationDPKRIITYNEAMDSP
CCCCEEECHHHCCCC		10.7025619855
689PhosphorylationTYNEAMDSPDQ----
ECHHHCCCCCC----		19.7925521595
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NUFP2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NUFP2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NUFP2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of NUFP2_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NUFP2_MOUSE

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry.";
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.;
Mol. Cell. Proteomics 8:904-912(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-649, AND MASSSPECTROMETRY.
"The phagosomal proteome in interferon-gamma-activated macrophages.";
Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,Thibault P.;
Immunity 30:143-154(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-649, AND MASSSPECTROMETRY.
"Large-scale phosphorylation analysis of mouse liver.";
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-213 ANDSER-215, AND MASS SPECTROMETRY.
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations.";
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
Mol. Cell. Proteomics 6:283-293(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-649, AND MASSSPECTROMETRY.
"Phosphoproteomic analysis of the developing mouse brain.";
Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.;
Mol. Cell. Proteomics 3:1093-1101(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory