NUB1_MOUSE - dbPTM
NUB1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NUB1_MOUSE
UniProt AC P54729
Protein Name NEDD8 ultimate buster 1
Gene Name Nub1
Organism Mus musculus (Mouse).
Sequence Length 614
Subcellular Localization Nucleus. Predominantly nuclear..
Protein Description Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation (By similarity)..
Protein Sequence MAQKKYLQAKLTQFLREDRIQLWKPPYTKENKEVGLAVKDLAKKYSERLECCENEVENIIEEIRRKAIERGTGNEHYRTTGIATIEVFLPPRLRKHDKKSLLETRLHVTGRDLRCQIAETFGFQENYIKIVINKKQLQLGKSLEEQGVTHNVKAMVLELKQSEEDVRKNLQLEEEEQNEAELKERRIQRTKRGLEILAERAEMVVDPETMPYLDIANQTGRSLRIPPAERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADRYFCECKELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIQNYHSGNGEEAREYLNKARQLFKELYIDPSKVHNLLQLGFTAQEARLGLRACDGNVDHAATHISNRREELAQIRKEEKEKRRRRLENVNTLRGMGYSTQAAKQALHQARGNLDDALKVLLSNPHMWWLQDADPENNSRQASPSQESINQLVYMGFDTVVAEAALRVFGGNVQLAAQTLAHHGGSLPPDLQFSGEDSSPTPSTSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEVIIAEYLSYVESISSAAKNN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
24MalonylationEDRIQLWKPPYTKEN
HHHHHHCCCCCCCCC		44.7126320211
28PhosphorylationQLWKPPYTKENKEVG
HHCCCCCCCCCHHHH		37.3424759943
142PhosphorylationKQLQLGKSLEEQGVT
HHHHHCCCHHHCCCC		38.9328973931
162PhosphorylationMVLELKQSEEDVRKN
HEEEHHHCHHHHHHH		41.1728066266
168UbiquitinationQSEEDVRKNLQLEEE
HCHHHHHHHCHHCHH		62.9522790023
183UbiquitinationEQNEAELKERRIQRT
HHHHHHHHHHHHHHH		40.4522790023
311UbiquitinationKKLNLAQKCFKNCYG
HHHHHHHHHHHHCCC		35.7122790023
314UbiquitinationNLAQKCFKNCYGENH
HHHHHHHHHCCCCCC		56.4222790023
328UbiquitinationHQRLVHIKGNCGKEK
CCEEEEEECCCCHHH		29.2322790023
335AcetylationKGNCGKEKVLFLRLY
ECCCCHHHHHHHHHH		47.9623236377
361PhosphorylationNGEEAREYLNKARQL
CHHHHHHHHHHHHHH		15.2628576409
370UbiquitinationNKARQLFKELYIDPS
HHHHHHHHHHCCCHH		56.2422790023
399S-nitrosocysteineARLGLRACDGNVDHA
HHHCHHCCCCCCCHH		5.79-
399S-nitrosylationARLGLRACDGNVDHA
HHHCHHCCCCCCCHH		5.7921278135
437PhosphorylationRRLENVNTLRGMGYS
HHHHHHHHHCCCCCC		17.3529176673
443PhosphorylationNTLRGMGYSTQAAKQ
HHHCCCCCCHHHHHH		10.3130635358
444PhosphorylationTLRGMGYSTQAAKQA
HHCCCCCCHHHHHHH		14.3330635358
445PhosphorylationLRGMGYSTQAAKQAL
HCCCCCCHHHHHHHH		17.4730635358
449UbiquitinationGYSTQAAKQALHQAR
CCCHHHHHHHHHHHC		38.8422790023
484PhosphorylationDADPENNSRQASPSQ
CCCCCCCCCCCCCCH		37.0327180971
488PhosphorylationENNSRQASPSQESIN
CCCCCCCCCCHHHHH		19.4227180971
490PhosphorylationNSRQASPSQESINQL
CCCCCCCCHHHHHHH		44.0527600695
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NUB1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NUB1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NUB1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NUB1_MOUSE

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Related Literatures of Post-Translational Modification

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