NU301_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NU301_CAEEL
• UniProt AC: Q6BER5
• Protein Name: Nucleosome-remodeling factor subunit NURF301-like
• Gene Name: nurf-1
• Organism: Caenorhabditis elegans.
• Sequence Length: 2194
• Subcellular Localization: Nucleus .
• Protein Description: Histone-binding component of a NURF-like (nucleosome remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates..
• Protein Sequence: MAPPRGRSKRKHPSESGNSSIADSEDPSESTSSSRPRRSRLPKRYFDDGYSPPPTKKRAAQRETPSDAEEVEVKIEEISVRSTPASTPAPKSTSKARGRPKKNPTPPRRKSLKRQEEDIIYMDEDSEEEEESSDDEFMLNEDQVVQEEEEELNLTDIKIEKGLDEENKYCPWLDEDPASLPKLELPESSQDIPIPTASIMDAVEIYEILRSYHRTLRITPFTFEDFCAALISHNNSCIMAEVHMALLRNCLKSDDEEQTHYSVTETNNSVNIMIHHMDTLTYAEILRQYIEAYPFADASVRDAINVDNYPFVGYDAKLVVLLFMSYRFLYSSEFKKLVNNVGKFQNDENCRVCGKSSGRVVGCTQCEAAFHVECSHLKPFPEVLVCNICKKNSAVRGVLPPDEAVDREPLRSQPIGRDRYGRYYWFIVRRLVVQSLDETELYYYSTVPQLYQLLQKLDRTYYEKDLCDTIRLRIDEFLEQMALTVEMTSERREAALETMVKRQLIGYDFAEATTPQIYLHRDSMKRMASILRDCAQKGQVKQEVKLEEPVEGQSPVKCVQFVEDSILPESMIGIFDAKLINTFWSGGATQEELVEQFVDISDNFDAPSANLWRMGDEGNDQTFMTYYNYYSRNEMSESFLTRKKAADKKKYMASKFAQIDNFDWVVAKNRQFYGDASLHCKFIMWTLQQVIKNIPIDLMHRKWPEFAKGFDLEVSVADDYKKLVTCLLKLDCAVRKTIFMPQWWNGLGQTRLERITVDQRENFMKEQQRLKKIDADALTKDLDDSFVRVNYMKPKWPNTYILRQRGETYRNAGKGSMGGWAWVAAKYVEKWIQVPESPKLPLAVTVEEIKTESVSNRKARRLELLVSKITKKRQRSGGKSSKKPTFELTNGCYSPSCRSNPNRKCYSPMCRNGYLVSAKQAHDERKLEESGVLGEEKAWPIPEIQTFSTKRGGKSIFVLQKKILRQMIMGGGCQQVYMPGFSAGIKSNLLIWPYPAPRPTLDLCWKWQTLNARSLHAVALQLKIIWSSIKFNEFDPDDTHPDRRVVIDTPSHDERRRIIRHKEMPPYGQYERYEMEIEIIPLYDEPEEEDESWLSRNRGGSSEFSHRSSSARKKRPQRSLDNRRATAIRREWVDGVTLKVFEIKDYWKWIRAEAEKTAKRKLEATRKAQKAKEDEERRRIQQQQQRSVARIPVPMHSLIPSERNNVPYLGSQQQRRPNGNERGFLEKYNNSSSVSPQAHGYASTPPPGYHQPQPNIIRQAGYNQLPRKPTTSPFNFQSRPVATIPTTPQLRAAAGADGVVRAVMMTPGNKSTVNTNSTPYPQALNRQQYQLQRQQQQPAVRRLTNGYHFMDGTMRGGGRNPSVQMHQRLPQNRAALQRPFGESTTEMRRVTEAAIPDNDGDEQPPVIPRYDPTSNFDAQRAQQQHPQSRPVYSTPAQMIRTTQPGGVKHNVILMKASDGTQKMVLKPGQFPPGTVISTGQRVVPYRQPTAVQQRQLYTATPGTRVVRIPNANGGAPRQQDHQVMRRVVQASGPRAMEYMDDQGTPPPGQQVRYVLQGGNSGTPNVNPPKVSSRGGPRGGLTMQMVQQQQQHNPEHRRLLAGRQKQKVTTYRDFMASRGYLDTSKFMMQTKPTFLPFEFNEEEEREINEAIAREEAWMRQEEENKTSGYDSSGNPIRSITSSGDTQRAPPYVSNLLPSSNDSPDDKVIKQVLDVMFSQVCRWDRQYGWSKTHVKRARQKNDSDKMHLRKFRMNQRELLITDHMERLKKEINKRRTRMENEAEQQCGLLTPWRKARARPHRAAKPKAEVKKEVINPADITLGGDTYDYVKEQKPTESIATNVSRRRRTSANLSKSEDDRDKPESQSTAPKSKERRTSEPPASHVAFHTPGSATPHDINLSIEHCTCQKIFDASKLYIQCELCARWYHGDCVGVAEQTILGLEHWSCEECIEEQERVKDQPALYCVCQKPYDDTKFYVGCDSCQGWFHPECVGTTRAEAEQAADYNCPACTREAEGYESEASDVSGSSRVSVQLTRADYTHVFELLELLLEHRMSTPFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQMFENAKTYNPKGNAVFKCAETMQEVFDKKLIDVREQMTARQQMLLLATAQQQDPMSSIRKRVQSESQRTVDSLDIDSDQLLPLDANLMRLYDF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	KRYFDDGYSPPPTKK CHHCCCCCCCCCCHH	3.15	30078680
51	Phosphorylation	RYFDDGYSPPPTKKR HHCCCCCCCCCCHHH	33.29	30078680
64	Phosphorylation	KRAAQRETPSDAEEV HHHCCCCCCCCHHHC	39.37	26392051
66	Phosphorylation	AAQRETPSDAEEVEV HCCCCCCCCHHHCEE	43.70	26392051
120	Phosphorylation	KRQEEDIIYMDEDSE HCCHHCCEEECCCCH	30.22	19530675
122	Phosphorylation	QEEDIIYMDEDSEEE CHHCCEEECCCCHHH	57.80	19530675
554	Phosphorylation	EEPVEGQSPVKCVQF CCCCCCCCCCEEEEE	10.36	28854356
626	Phosphorylation	NDQTFMTYYNYYSRN CCCCEEHHHEECCCC	42.38	19530675
1102	Phosphorylation	SRNRGGSSEFSHRSS HCCCCCCCCCCCCCC	44.05	28854356
1846	Phosphorylation	NVSRRRRTSANLSKS HHHHHHHHCCCCCCC	38.10	19530675
1847	Phosphorylation	VSRRRRTSANLSKSE HHHHHHHCCCCCCCC	28.71	19530675
1919	Phosphorylation	KLYIQCELCARWYHG HHHHEEHHHHHHCCC	17.22	19530675

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NU301_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NU301_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NU301_CAEEL !!

Protein-Protein Interaction

Oops, there are no PPI records of NU301_CAEEL !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.