dbPTM

NTNG2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NTNG2_HUMAN
UniProt AC	Q96CW9
Protein Name	Netrin-G2
Gene Name	NTNG2
Organism	Homo sapiens (Human).
Sequence Length	530
Subcellular Localization	Cell membrane Lipid-anchor, GPI-anchor Extracellular side .
Protein Description	Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites..
Protein Sequence	MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
122	N-linked_Glycosylation	YPSPLEANITLSWNK CCCCCEEEEEEEECC	20.57	22041449
128	N-linked_Glycosylation	ANITLSWNKTVELTD EEEEEEECCEEEECC	27.09	22041449
248	Phosphorylation	KGLKEFFTLTDLRMR CCHHHHHHHHHHHHH	33.78	26437602
310	N-linked_Glycosylation	LQCECEHNTTGPDCG EEEEEECCCCCCCCC	19.62	UniProtKB CARBOHYD
332	Phosphorylation	TRSWRAGSYLPLPHG CCCEECCCCCCCCCC	23.63	19690332
333	Phosphorylation	RSWRAGSYLPLPHGS CCEECCCCCCCCCCC	16.06	19690332
340	Phosphorylation	YLPLPHGSPNACATA CCCCCCCCCCCCCCC	16.37	19690332
395	N-linked_Glycosylation	CRLGYYRNGSAELDD CCCCCCCCCCCCCCC	32.42	UniProtKB CARBOHYD
422	N-linked_Glycosylation	GSVHDRCNETGFCEC CCCCHHHCCCCCEEE	51.24	UniProtKB CARBOHYD
507	GPI-anchor	LDCDRAPGAAPRPAT CCCCCCCCCCCCHHH	33.13	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NTNG2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NTNG2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NTNG2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NTNG2_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NTNG2_HUMAN

Related Literatures of Post-Translational Modification