NT102_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NT102_ARATH
• UniProt AC: Q9M2Q4
• Protein Name: RNA cytidine acetyltransferase 2 {ECO:0000255|HAMAP-Rule:MF_03211}
• Gene Name: At3g57940
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1028
• Subcellular Localization: Nucleus, nucleolus .
• Protein Description: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation..
• Protein Sequence: MRKKVDERIRTLIENGVKLRHRSMFVIIGDKSRDQIVNLHHMLSKAVIKCNPSVLWCYKDKLDISSHKQKRSKQLKRLRERGQLDPEKLDAFSRLLDVGRVTHCLYKDSERILGNTFGMCILQDFEALTPNLLARTIETVEGGGLVVLILRSLTSLTSLCTMVMDVHDRFRTESHSEAAGRFNERFLLSLASCKACVVMDDELNILPLSSHIRSITQVPTEKDSEGLSEAERDLKSLKEDLSDDFPVGPLIKKCCTLDQGKAVVTFFDAILDKALRSIVALIASRGRGKSAALGLAVAGAVAAGYSNIYITAPSPDNLKTFFEFVCKGFDALEYKEHLDYDVVKSANPDFKKAVVRINIFKQHRQTIQYIQPHEHEKLSQVELLVIDEAAAIPLPVVKSLLGPYLVFLSSTVSGYEGTGRSLSLKLLQQLDEQSRAPATGLEGSGCLFKKIELTESIRYGSGDPIESWLNGLLCLDVATCLPNPACHPSPSQCDLYYVNRDTLFSYHKDSELFLQRMMALCVSSHYKNSPNDLQLLADAPAHHLFVLLGPVDESQNKIPDILCVIQVCLEGKISENSALQSLRDGHSPYGDQIPWKFCEQFRDTEFPGFSGARIVRIAVHPNAMKMGYGSAAVELLTRYFEGQIAPISEAEDKVDVEHAPIKVTEAAEKVSMLEEQVKPRTNLPPLLVPLHDRRPEKLHYIGVSFGLTLDLFRFWRKHNFAPFYVSQIPSAVTGEHTCMLLKPLKNDELEVNESDELGFFTPFYKDFKIRFSKLLSDKFKKMDYKLAMSVLNPKINFAEVDSSGSSSGGFLKTLNGILSPYDMERLRAYTENLTDFNLVYDICKTLAHQYFEEKLPVSLSYVQASILLCLGLQETDFSSIERQMQLERGQIHSLLLKVARELYKYLNGVAGKEIKSALPRLKERELTAHNVSVDDDIREGAKQVEEQMKKEKIEGLMDSELQQYVIGDKEAEALQHSKISSSGIISVKSTKSENENGFDKSTKKRSSDKRSSSSSKSKSSKKRKSLKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	GVKLRHRSMFVIIGD CCCCCCCCEEEEEEC		25561503
172	Phosphorylation	DVHDRFRTESHSEAA CHHHHHCCCCHHHHC		28295753
176	Phosphorylation	RFRTESHSEAAGRFN HHCCCCHHHHCCCCC		28295753
423	Phosphorylation	EGTGRSLSLKLLQQL CCCCHHHHHHHHHHH		28011693
454	Phosphorylation	LFKKIELTESIRYGS EEEEEEECCCCCCCC		19880383
456	Phosphorylation	KKIELTESIRYGSGD EEEEECCCCCCCCCC		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NT102_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NT102_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NT102_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of NT102_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.