| UniProt ID | NSUN5_MOUSE | |
|---|---|---|
| UniProt AC | Q8K4F6 | |
| Protein Name | Probable 28S rRNA (cytosine-C(5))-methyltransferase | |
| Gene Name | Nsun5 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 465 | |
| Subcellular Localization | ||
| Protein Description | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 28S rRNA.. | |
| Protein Sequence | MGLYAAAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFSYQGRASSLEDLRALKGQHFLLDPLLPELLVFPAQTDLHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQGKIFAFDQDAKRLAAMATLVARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGMLSRQLEEHGEGTPSKERLQALAGFQQRALCHALRFPSLQRLVYSTCSLCQEENEDVVQEALQHNSGTFRLAPVLPTWPHRGLSTFPGSEHCLRASPETTLTGGFFIAVFERAEVVPTPAPQTDAMDPEPLSQVPKRKRRRKAAVGASMQPST | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MGLYAAAAA ------CCHHHHHHH | 27.65 | - | |
| 166 | Phosphorylation | FSYQGRASSLEDLRA CCCCCCCCCHHHHHH | 33.81 | 28066266 | |
| 167 | Phosphorylation | SYQGRASSLEDLRAL CCCCCCCCHHHHHHH | 34.49 | 23737553 | |
| 228 | Phosphorylation | LLSPPPGSHVIDACA HCCCCCCCCHHHHCC | 21.98 | - | |
| 242 | Phosphorylation | AAPGNKTSYIAALLK CCCCCHHHHHHHHHH | 19.02 | - | |
| 288 | Phosphorylation | LAEKDFLTVSPSDQR HHHHCCEECCCCCCC | 20.94 | 28066266 | |
| 290 | Phosphorylation | EKDFLTVSPSDQRYS HHCCEECCCCCCCCE | 17.28 | 28066266 | |
| 292 | Phosphorylation | DFLTVSPSDQRYSQV CCEECCCCCCCCEEE | 38.58 | 28066266 | |
| 307 | Phosphorylation | QYILLDPSCSGSGML EEEEECCCCCCCCHH | 22.15 | - | |
| 309 | Phosphorylation | ILLDPSCSGSGMLSR EEECCCCCCCCHHHH | 40.09 | - | |
| 311 | Phosphorylation | LDPSCSGSGMLSRQL ECCCCCCCCHHHHHH | 12.53 | - | |
| 325 | Phosphorylation | LEEHGEGTPSKERLQ HHHCCCCCCCHHHHH | 21.78 | 25338131 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NSUN5_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NSUN5_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NSUN5_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of NSUN5_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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