NS1BP_MOUSE - dbPTM
NS1BP_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NS1BP_MOUSE
UniProt AC Q920Q8
Protein Name Influenza virus NS1A-binding protein homolog
Gene Name Ivns1abp
Organism Mus musculus (Mouse).
Sequence Length 642
Subcellular Localization Isoform 1: Cytoplasm. Cytoplasm, cytoskeleton . Associated with actin filaments.
Isoform 2: Nucleus . Not associated with actin filaments (PubMed:15684717).
Protein Description Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. [PubMed: 12213805]
Protein Sequence MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGVSHVKLDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNPLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISGSSTGCLSSPNASMQSPKHEWKIVASEKTSNNTYLCLAVLDSTFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQPDELLEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNPQSNEWSPYTKIFQF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
193UbiquitinationVCLPSNGKLYTKVIN
EEECCCCEEHHHHHH		42.4422790023
197UbiquitinationSNGKLYTKVINWVQR
CCCEEHHHHHHHHHH		27.7922790023
246PhosphorylationGQAEVFGSDDDHIQF
CCCEECCCCCCCEEE		26.8027087446
268PhosphorylationENGHKQISGSSTGCL
CCCCCCCCCCCCCCC		30.0825619855
270PhosphorylationGHKQISGSSTGCLSS
CCCCCCCCCCCCCCC		20.2425619855
271PhosphorylationHKQISGSSTGCLSSP
CCCCCCCCCCCCCCC		32.1425619855
272PhosphorylationKQISGSSTGCLSSPN
CCCCCCCCCCCCCCC		33.3425619855
276PhosphorylationGSSTGCLSSPNASMQ
CCCCCCCCCCCCCCC		48.0725619855
277PhosphorylationSSTGCLSSPNASMQS
CCCCCCCCCCCCCCC		14.8225619855
281PhosphorylationCLSSPNASMQSPKHE
CCCCCCCCCCCCCCE		24.8025619855
284PhosphorylationSPNASMQSPKHEWKI
CCCCCCCCCCCEEEE		27.5525619855
322PhosphorylationIFLHGRNSPQSSPTS
EEECCCCCCCCCCCC		23.9725521595
325PhosphorylationHGRNSPQSSPTSTPK
CCCCCCCCCCCCCCC		41.4925521595
326PhosphorylationGRNSPQSSPTSTPKL
CCCCCCCCCCCCCCC		27.2725521595
328PhosphorylationNSPQSSPTSTPKLSK
CCCCCCCCCCCCCCC		47.3725521595
329PhosphorylationSPQSSPTSTPKLSKS
CCCCCCCCCCCCCCC		46.2025159016
330PhosphorylationPQSSPTSTPKLSKSL
CCCCCCCCCCCCCCC		27.2425521595
334PhosphorylationPTSTPKLSKSLSFEM
CCCCCCCCCCCCCCC		26.7324759943
336PhosphorylationSTPKLSKSLSFEMQP
CCCCCCCCCCCCCCH		26.3527742792
338PhosphorylationPKLSKSLSFEMQPDE
CCCCCCCCCCCCHHH		26.6726824392
352PhosphorylationELLEKPMSPMQYARS
HHHHCCCCHHHHHHC		26.2525159016
356PhosphorylationKPMSPMQYARSGLGT
CCCCHHHHHHCCCCC		9.5725777480
369UbiquitinationGTAEMNGKLIAAGGY
CCHHHCCEEEEECCC		31.5422790023
477UbiquitinationGSDPYGQKGLKNCDV
CCCCCCCCCCCCCCC		62.9422790023
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NS1BP_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NS1BP_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NS1BP_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of NS1BP_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NS1BP_MOUSE

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Related Literatures of Post-Translational Modification

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