UniProt ID | NRT_DROME | |
---|---|---|
UniProt AC | P23654 | |
Protein Name | Neurotactin | |
Gene Name | Nrt | |
Organism | Drosophila melanogaster (Fruit fly). | |
Sequence Length | 846 | |
Subcellular Localization |
Membrane Single-pass type II membrane protein . Expressed in membranes during embryogenesis. |
|
Protein Description | May mediate or modulate cell adhesion between embryonic cells during development.. | |
Protein Sequence | MGELEEKETPPTETTAAQQEALEEPKETDKMLDKKEDAKEKTPSPQTSKPASPNAGKKSSPVAEKKIDDAELAKSKSGNGEEIIDIPAENGTKPDSADDKKISKEEREVKPKKIPIGGLKLPGFFMKNKPKADGDGAEGELLEKEKEEDKDKEANGDAATGSGKDEQKSRPGLGERLRSFFARKPSAEKEKKQLVNGDADAKSEATAEATPAEDASDAPPKRGLLNAIKLPIANMIPKKKSNDDVELGLGKAGLASMETLDDSLKDQDTVDRAPVKTNGTEELKGELKDEKLAAEEKLAAEEEEQNRPVSLLTRLRGYKCSVDDALIVFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEGVKEDGAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTVGDEDCLYLDVVTPHVRYNNPLPVVVLIGAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATLECADIQCLREASSERLWAATPDTWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHEAHTEKLRELHANWTREEVRAYLENSQIGALGLTDEVIEKYNASSYASLVSIISDIRSVCPLLTNARQQPSVPFYVVTQGEGPDQLATVDADVQAILGRYEPHTVEQRRFVSAMQQLFYYYVSHGTVQSFVQNRRVINVGQDAQPEEDYLPCNYWISKDIVPRYARVD | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
28 | Phosphorylation | ALEEPKETDKMLDKK HHHCCHHHHHHHHHH | 47.23 | - | |
42 | Phosphorylation | KEDAKEKTPSPQTSK HHHHHHCCCCCCCCC | 30.04 | 22817900 | |
44 | Phosphorylation | DAKEKTPSPQTSKPA HHHHCCCCCCCCCCC | 34.57 | 22817900 | |
47 | Phosphorylation | EKTPSPQTSKPASPN HCCCCCCCCCCCCCC | 41.94 | 22817900 | |
48 | Phosphorylation | KTPSPQTSKPASPNA CCCCCCCCCCCCCCC | 31.25 | 22817900 | |
52 | Phosphorylation | PQTSKPASPNAGKKS CCCCCCCCCCCCCCC | 27.49 | 22817900 | |
60 | Phosphorylation | PNAGKKSSPVAEKKI CCCCCCCCCCHHHHC | 32.07 | 27794539 | |
75 | Phosphorylation | DDAELAKSKSGNGEE CHHHHHHCCCCCCCE | 26.84 | - | |
77 | Phosphorylation | AELAKSKSGNGEEII HHHHHCCCCCCCEEE | 44.58 | 18327897 | |
103 | Phosphorylation | SADDKKISKEEREVK CCCCCCCCHHHHCCC | 42.78 | - | |
169 | Phosphorylation | SGKDEQKSRPGLGER CCCCHHHCCCCHHHH | 43.32 | - | |
186 | Phosphorylation | SFFARKPSAEKEKKQ HHHHCCCCCHHHHHH | 52.69 | - | |
203 | Phosphorylation | NGDADAKSEATAEAT CCCCCHHHHHCHHCC | 33.90 | 22817900 | |
206 | Phosphorylation | ADAKSEATAEATPAE CCHHHHHCHHCCCCH | 22.45 | 22817900 | |
216 | Phosphorylation | ATPAEDASDAPPKRG CCCCHHCCCCCCCCC | 46.78 | 27794539 | |
241 | Phosphorylation | NMIPKKKSNDDVELG HCCCCCCCCCCCCCC | 55.13 | 27794539 | |
256 | Phosphorylation | LGKAGLASMETLDDS CCHHHHHHHHHHCHH | 23.38 | 22817900 | |
259 | Phosphorylation | AGLASMETLDDSLKD HHHHHHHHHCHHHCC | 27.18 | 22817900 | |
263 | Phosphorylation | SMETLDDSLKDQDTV HHHHHCHHHCCCCCC | 36.66 | 22817900 | |
269 | Phosphorylation | DSLKDQDTVDRAPVK HHHCCCCCCCCCCCC | 20.76 | 22817900 | |
410 | N-linked_Glycosylation | DDINMCWNDTLQTHN HHHCCHHHHHHHHCC | 27.71 | - | |
417 | N-linked_Glycosylation | NDTLQTHNSSVVCTQ HHHHHHCCCEEEEEE | 39.09 | - | |
428 | N-linked_Glycosylation | VCTQRLGNGTTVGDE EEEEECCCCCEECCC | 49.59 | - | |
611 | Phosphorylation | QCLREASSERLWAAT HHHHHHCCCCCEEEC | 33.51 | 22668510 | |
636 | N-linked_Glycosylation | LPQPQEANASGSRHE CCCCCCCCCCCCCCE | 33.61 | - | |
691 | N-linked_Glycosylation | KLRELHANWTREEVR HHHHHHHCCCHHHHH | 29.88 | - | |
720 | N-linked_Glycosylation | DEVIEKYNASSYASL HHHHHHHCCCCHHHH | 44.40 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
28 | T | Phosphorylation | Kinase | PKC | - | Uniprot |
75 | S | Phosphorylation | Kinase | PKC | - | Uniprot |
103 | S | Phosphorylation | Kinase | PKC | - | Uniprot |
169 | S | Phosphorylation | Kinase | PKC | - | Uniprot |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NRT_DROME !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NRT_DROME !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
RS27A_DROME | RpS27A | physical | 24292889 | |
NRG_DROME | Nrg | genetic | 9491984 | |
ABL_DROME | Abl | genetic | 12783792 | |
AMAL_DROME | Ama | physical | 10970840 | |
AMAL_DROME | Ama | physical | 12783792 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
loading...
Phosphorylation | |
Reference | PubMed |
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-42; SER-44; THR-47;SER-48; SER-52; SER-77; SER-203; THR-206; SER-256; THR-259; SER-263AND THR-269, AND MASS SPECTROMETRY. |