dbPTM

NRIP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NRIP2_HUMAN
UniProt AC	Q9BQI9
Protein Name	Nuclear receptor-interacting protein 2
Gene Name	NRIP2
Organism	Homo sapiens (Human).
Sequence Length	281
Subcellular Localization	Nucleus.
Protein Description	Down-regulates transcriptional activation by nuclear receptors such as NR1F2..
Protein Sequence	MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQVEQLELQLGQETVVCSAQVVDAESPEFCLGLQTLLSLKCCIDLEHGVLRLKAPFSELPFLPLYQEPGQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
89	Phosphorylation	QRRLKQATQFLHKDS HHHHHHHHHHHHHCC	19.84	28857561
96	Phosphorylation	TQFLHKDSADLLPLD HHHHHHCCCCCCCHH	28.61	26657352
104	Phosphorylation	ADLLPLDSLKRLGTS CCCCCHHHHHHHCCC	43.40	23312004
110	Phosphorylation	DSLKRLGTSKDLQPR HHHHHHCCCCCCCCH	36.88	28857561
111	Phosphorylation	SLKRLGTSKDLQPRS HHHHHCCCCCCCCHH	23.52	28857561
152	Phosphorylation	GQESRRKTSRTEIPA CHHHHCCCCCCCCCH	22.94	26657352
153	Phosphorylation	QESRRKTSRTEIPAL HHHHCCCCCCCCCHH	39.99	28857561
155	Phosphorylation	SRRKTSRTEIPALLV HHCCCCCCCCCHHHH	37.73	28857561
249	Phosphorylation	LGLQTLLSLKCCIDL HHHHHHHHHHHHHCC	28.97	24719451
276	Phosphorylation	ELPFLPLYQEPGQ-- HCCCEECCCCCCC--	14.64	26503514

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NRIP2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NRIP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NRIP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NRIP2_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NRIP2_HUMAN

Related Literatures of Post-Translational Modification