| UniProt ID | NRBP2_HUMAN | |
|---|---|---|
| UniProt AC | Q9NSY0 | |
| Protein Name | Nuclear receptor-binding protein 2 | |
| Gene Name | NRBP2 {ECO:0000312|HGNC:HGNC:19339} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 501 | |
| Subcellular Localization | Cytoplasm. | |
| Protein Description | May regulate apoptosis of neural progenitor cells during their differentiation.. | |
| Protein Sequence | MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIFSFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPTDSAQDLASELVHYGFLHEDDRMKLAAFLESTFLKYRGTQA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 22 | Phosphorylation | EREREDESEDESDIL HHHHCCCCCCHHHHH | 63.77 | 23401153 | |
| 26 | Phosphorylation | EDESEDESDILEESP CCCCCCHHHHHHHCC | 42.12 | 29255136 | |
| 32 | Phosphorylation | ESDILEESPCGRWQK HHHHHHHCCCCHHHH | 19.00 | 23927012 | |
| 193 | Phosphorylation | NGLIKIGSVWHRIFS CCEEEECHHHHHHHC | 26.05 | 28857561 | |
| 209 | Phosphorylation | ALPDDLRSPIRAERE CCCHHHCCCHHHHHH | 31.79 | 28192239 | |
| 247 (in isoform 4) | Phosphorylation | - | 3.83 | 25954137 | |
| 248 (in isoform 4) | Phosphorylation | - | 13.43 | 25954137 | |
| 253 (in isoform 4) | Phosphorylation | - | 26.84 | 25954137 | |
| 273 | Phosphorylation | AIARARHSLSDPNMR HHHHHHHHCCCCCHH | 24.82 | 25690035 | |
| 296 | Phosphorylation | RDPARRPSAHSLLFH CCCCCCCCHHHHHHH | 36.48 | 28857561 | |
| 360 | Phosphorylation | RPPLQWRYSEVSFME CCCCCCCCEEECHHH | 13.26 | 22985185 | |
| 361 | Phosphorylation | PPLQWRYSEVSFMEL CCCCCCCEEECHHHH | 23.97 | 28857561 | |
| 364 | Phosphorylation | QWRYSEVSFMELDKF CCCCEEECHHHHHHH | 18.15 | 28857561 | |
| 409 | Phosphorylation | EEVQKAKTPTPEPFD HHHHCCCCCCCCCCC | 36.94 | 30266825 | |
| 411 | Phosphorylation | VQKAKTPTPEPFDSE HHCCCCCCCCCCCHH | 45.58 | 30266825 | |
| 417 | Phosphorylation | PTPEPFDSETRKVIQ CCCCCCCHHHHHHEE | 41.04 | 30266825 | |
| 419 | Phosphorylation | PEPFDSETRKVIQMQ CCCCCHHHHHHEEHH | 39.48 | 30266825 | |
| 421 | Ubiquitination | PFDSETRKVIQMQCN CCCHHHHHHEEHHHC | 51.62 | 29967540 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NRBP2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NRBP2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NRBP2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of NRBP2_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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