NPM3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NPM3_MOUSE
• UniProt AC: Q9CPP0
• Protein Name: Nucleoplasmin-3
• Gene Name: Npm3
• Organism: Mus musculus (Mouse).
• Sequence Length: 175
• Subcellular Localization: Nucleus.
• Protein Description: May act as a chaperone..
• Protein Sequence: MAAGAAAALAFLNQESRARAGGVGGLRVPAPVTMDSFFFGCELSGHTRSFTFKVEEEDDTEHVLALNMLCLTEGATDECNVVEVVARDHDNQEIAVPVANLRLSCQPMLSVDDFQLQPPVTFRLKSGSGPVRITGRHQIVCINNDLSEEESDDESEEDEIKLCGILPAKKHRGRP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAGAAAAL ------CHHHHHHHH	18.01	-
16	Phosphorylation	LAFLNQESRARAGGV HHHHCHHHHHHCCCC	22.83	22817900
27	Methylation	AGGVGGLRVPAPVTM CCCCCCCCCCCCEEE	35.33	-
41	S-nitrosocysteine	MDSFFFGCELSGHTR ECEEEECEEECCCEE	3.93	-
41	S-nitrosylation	MDSFFFGCELSGHTR ECEEEECEEECCCEE	3.93	20925432
147	Phosphorylation	VCINNDLSEEESDDE EEEECCCCCCCCCCC	45.91	27087446
151	Phosphorylation	NDLSEEESDDESEED CCCCCCCCCCCCHHH	54.35	27087446
155	Phosphorylation	EEESDDESEEDEIKL CCCCCCCCHHHHHHH	53.96	27087446

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NPM3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NPM3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NPM3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NPM3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.