dbPTM

NPL4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NPL4_SCHPO
UniProt AC	Q9P780
Protein Name	Nuclear protein localization protein 4
Gene Name	npl4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	572
Subcellular Localization	Cytoplasm, perinuclear region. Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side. Nucleus membrane Peripheral membrane protein Cytoplasmic side. Localizes mainly at the nuclear periphery and the endoplasmic reticulum mem
Protein Description	Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)..
Protein Sequence	MILRFRSKRGMARAEFQPTDTLAMLSAKILSDILKNDYSPENVSLCQNESDQGVIFSNLNDQTLQDAGLTHGQMLYLRLGTPNSDIASSNNEPALTVTGAPKQVSTPDVSEKKPSMPVIQDPIDDSLEKEDGLIRRSMTSLCRHGPKGMCDYCSPLEPYDESYRQENKIKHLSFHAYLRKINSNVNKYASSQSFIPPLEEPSFTVKEKCPSGHPPWPAGICTKCQPSTVMLNLQPFRVIDHIEFASPGIVDSFLNKWRQSGFQRIGYTYGHFEQYNNVPLGIKGVIEAIYEPPQVSEADGVTLEEWADEALVEQVATACGLRRIGIIFTDLTDDGSNSGKVLCKRHSDSYFLSSLEVYNSANFQTKFKNPCKWSRSGYFGSKFVTSVISGNLNGEIEVMSYQVSNIGTALYQADLIQPSVDPDRMLVKKEDQTRYVPDVLYRYTDKYGKQVSENAKPAFPVSFLLVTLTDGFPEKPDPLFSNNDTSIITTLESTDETGRLRQLAKLFDHNAIANGSLSNFSVLLAIAKLSILGKDDLAALASYATAPTEENEKNLNSRESYQTLLAILYSSL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
106	Phosphorylation	GAPKQVSTPDVSEKK CCCCCCCCCCCCCCC	25.34	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NPL4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NPL4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NPL4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NPL4_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NPL4_SCHPO

Related Literatures of Post-Translational Modification