dbPTM

NPC3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NPC3_ARATH
UniProt AC	Q9SRQ6
Protein Name	Non-specific phospholipase C3
Gene Name	NPC3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	523
Subcellular Localization
Protein Description	Possesses specific phosphatase activity toward lysophosphatidic acid (LPA) in vitro. Does not show phospholipase C activity. May play a role in signal transduction and storage lipid synthesis. May be involved in brassinolide-mediated signaling in root development..
Protein Sequence	MVEETSSGGGSSASPIKTIVVLVQENRSFDHMLGWFKELNPEIDGVSESEPRSNPLSTSDPNSAQIFFGKESQNIDPDPGHSFQAIYEQVFGKPFSDESPYPDPKMNGFVQNAEAITKGMSEKVVMQGFPPEKLPVFKELVQEFAVCDRWFSSLPSSTQPNRLYVHAATSNGAFSNDTNTLVRGFPQRTVFESLEESGFTFGIYYQSFPNCLFYRNMRKLKYVDNFHQYHLSFKRHCKEGKLPNYVVIEPRYFKILSAPANDDHPKNDVVEGQNLVKEIYEALRASPQWNEILFVVVYDEHGGYYDHVPTPVIGVPNPDGLVGPEPYNFKFDRLGVRVPALLISPWIEPGTVLHEPNGPEPTSQFEHSSIPATLKKIFNLKSFLTKRDEWAGTLDAVINRTSPRTDCPVTLPELPRARDIDIGTQEEDEDLTDFQIELIQAAAVLKGDHIKDIYPFKLADKMKVLDAARYVEEAFTRFHGESKKAKEEGRDEHEIVDLSKGSTRHSTPKSFVQKLFSCLICDN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
5	Phosphorylation	---MVEETSSGGGSS ---CCCCCCCCCCCC	30407730
6	Phosphorylation	--MVEETSSGGGSSA --CCCCCCCCCCCCC	30407730
7	Phosphorylation	-MVEETSSGGGSSAS -CCCCCCCCCCCCCC	30407730
59	Phosphorylation	RSNPLSTSDPNSAQI CCCCCCCCCCCCCEE	26811356
153	Phosphorylation	VCDRWFSSLPSSTQP HHCHHHHCCCCCCCC	30407730
156	Phosphorylation	RWFSSLPSSTQPNRL HHHHCCCCCCCCCEE	24601666
157	Phosphorylation	WFSSLPSSTQPNRLY HHHCCCCCCCCCEEE	30407730
158	Phosphorylation	FSSLPSSTQPNRLYV HHCCCCCCCCCEEEE	24601666

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NPC3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NPC3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NPC3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NPC3_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NPC3_ARATH

Related Literatures of Post-Translational Modification