NP1L1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NP1L1_RAT
• UniProt AC: Q9Z2G8
• Protein Name: Nucleosome assembly protein 1-like 1
• Gene Name: Nap1l1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 390
• Subcellular Localization: Nucleus. Melanosome.
• Protein Description: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation..
• Protein Sequence: MADIDNKEQSELDQDLEDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVDTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFILEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSKTSFFNFFAPPEVPENGDLDDDXEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADIDNKEQ ------CCCCCHHHH	23.59	-
10	Phosphorylation	DIDNKEQSELDQDLE CCCHHHHHHHHHCCH	41.01	22673903
62	Phosphorylation	RLDGLVDTPTGYIES HHCCCCCCCCCHHHH	18.44	27097102
64	Phosphorylation	DGLVDTPTGYIESLP CCCCCCCCCHHHHHH	44.72	27097102
66	Phosphorylation	LVDTPTGYIESLPKV CCCCCCCHHHHHHHH	12.18	28432305
69	Phosphorylation	TPTGYIESLPKVVKR CCCCHHHHHHHHHHH	40.17	28432305
105	Ubiquitination	EVHDLERKYAVLYQP HHHHHHHHHHHHHHH	28.34	-
116	Acetylation	LYQPLFDKRFEIINA HHHHHHHHHHHHHHH	52.21	-
143	Phosphorylation	PDEEDEVSEELKEKA CCCCCHHCHHHHHHH	24.25	-
193	Acetylation	EHDEPILKHLKDIKV HCCHHHHHHHHHCEE	47.84	22902405
270	Acetylation	KGKNVTLKTIKKKQK CCCCEEEEEHHHHHH	38.55	22902405
358	5-glutamyl polyglycine	DDYDEEGEEADEEGE CCCCCCCHHCCHHCC	53.98	-
358	Formation of an isopeptide bond	DDYDEEGEEADEEGE CCCCCCCHHCCHHCC	53.98	-
359	5-glutamyl polyglycine	DYDEEGEEADEEGEE CCCCCCHHCCHHCCC	72.74	-
359	Formation of an isopeptide bond	DYDEEGEEADEEGEE CCCCCCHHCCHHCCC	72.74	-
387	Methylation	KDQNPAECKQQ---- CCCCHHHHHCC----	5.39	-
387	Farnesylation	KDQNPAECKQQ---- CCCCHHHHHCC----	5.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NP1L1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NP1L1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NP1L1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of NP1L1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.