NOP58_RAT - dbPTM
NOP58_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NOP58_RAT
UniProt AC Q9QZ86
Protein Name Nucleolar protein 58
Gene Name Nop58
Organism Rattus norvegicus (Rat).
Sequence Length 534
Subcellular Localization Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein Description Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity)..
Protein Sequence MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKKIVKEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASATLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGAENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEMEEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
27PhosphorylationKKLQEVDSLWKEFET
HHHHHHHHHHHHCCC		41.1123984901
34PhosphorylationSLWKEFETPEKANKI
HHHHHCCCHHHHHHH		41.91-
105PhosphorylationIKEKLNLSCIHSPVV
HHHHCCCHHCCHHHH		15.2223984901
109PhosphorylationLNLSCIHSPVVNELM
CCCHHCCHHHHHHHH		10.2423984901
203PhosphorylationKIISDNLTYCKCLQK
HHHHCCCHHHHHHHH		32.8823984901
204PhosphorylationIISDNLTYCKCLQKV
HHHCCCHHHHHHHHH		7.9623984901
304PhosphorylationRLIAHAGSLLNLAKH
HHHHHHHHHHHHHHH		30.3923984901
350PhosphorylationHASLVGQTSPKHKGK
EHHHCCCCCCCCCCH		40.8628432305
351PhosphorylationASLVGQTSPKHKGKI
HHHCCCCCCCCCCHH		24.8623984901
411AcetylationRKISGTGKALAKAEK
EECCCCCHHHHHHHH		39.81-
427PhosphorylationEHKSEVKTYDPSGDS
CCCCCCCEECCCCCC		38.0328689409
431PhosphorylationEVKTYDPSGDSTLPT
CCCEECCCCCCCCCC		52.9523984901
434PhosphorylationTYDPSGDSTLPTCSK
EECCCCCCCCCCCCC		35.0623984901
435PhosphorylationYDPSGDSTLPTCSKK
ECCCCCCCCCCCCCC		41.3123984901
438PhosphorylationSGDSTLPTCSKKRKI
CCCCCCCCCCCCCCH		32.3123984901
440PhosphorylationDSTLPTCSKKRKIEE
CCCCCCCCCCCCHHH		43.6323984901
507PhosphorylationHIKEEPLSEEEPCTS
CCCCCCCCCCCCCCC		54.3923712012
513PhosphorylationLSEEEPCTSTAVPSP
CCCCCCCCCCCCCCH		39.5727097102
514PhosphorylationSEEEPCTSTAVPSPE
CCCCCCCCCCCCCHH		22.5327097102
515PhosphorylationEEEPCTSTAVPSPEK
CCCCCCCCCCCCHHH		17.3327097102
519PhosphorylationCTSTAVPSPEKKKKK
CCCCCCCCHHHHHHH		38.8123712012
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NOP58_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NOP58_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NOP58_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of NOP58_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NOP58_RAT

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Related Literatures of Post-Translational Modification

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